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USUL SKRIPSI
PERBEDAAN FUNGSI KOGNITIF DENGAN SKORING MONTREALCOGNITIVE ASSESMENT (MoCA) PADA PASIEN STROKE HEMORAGIK DAN STROKE NON HEMORAGIK DI RUANG RAWAT INAP RSUD PROF. DR. MARGONO SOEKARJO PURWOKERTO
Oleh:
Meta Mukhsinina Purnama
G1A010064
KEMENTERIAN PENDIDIKAN DAN KEBUDAYAANUNIVERSITAS JENDERAL SOEDIRMAN
FAKULTAS KEDOKTERAN DAN ILMU-ILMU KESEHATANJURUSAN KEDOKTERAN
PURWOKERTO
2013
USUL SKRIPSI
HUBUNGAN POLA MAKAN DENGAN KADAR KOLESTEROL TOTAL PADA PASIEN STROKE ISKEMIK DI RSUD MARGONO SOEKARJO
PURWOKERTO
Diajukan Sebagai Pedoman Pelaksanaan Penelitian (Karya Tulis Ilmiah)
Pada Fakultas Kedokteran dan Ilmu Ilmu Kesehatan
Purwokerto
Disetujui dan disahkanPada tanggal, 2013
Pembimbing I Pembimbing II
dr. Muttaqien Pramudigyo, Sp.S. NIP. 19800413.200501.2.001
dr. Diah Krisnasari NIP 19760123.200501.1.002
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DAFTAR ISI
Halaman
DAFTAR GAMBAR.............................................................................................ivDAFTAR LAMPIRAN.............................. ...........................................................v
I. PENDAHULUAN A. Latar Belakang .......................................................................................... 1B. Perumusan Masalah .................................................................................. 5C. Tujuan Penelitian ....................... ............................................................... 5D. Manfaat Penelitian .................................................................................... 5
1. Manfaat teoritis ..................................................................................... 52. Manfaat praktis ..................................................................................... 5
II. TINJAUAN PUSTAKA ................................................................................... 6A. Stres ............................................................................................................. 6B. Model Stres Paradoxical Sleep Deprivation (PSD) Pada hewan
Coba............................................................................................................ 8C. Sel Leydig.................................................................................................. 10D. Pengaruh Stres terhadap Jumlah Sel Leydig ............................................. 11E. Peran Vitamin C dan Vitamin E sebagai Antioksidan...............................14
1. Vitamin C............................................................................................... 142. Vitamin E............................................................................................... 153. Kombinasi Vitamin C dan E.................................................................. 17
F. Kerangka Teori.......................................................................................... 19G. Kerangka Konsep...................................................................................... 20H. Hipotesis.................................................................................................... 20
III. METODE PENELITIAN............................................................................. 21A. Materi dan Bahan....................................................................................... 21
1. Hewan Coba.......................................................................................... 222. Alat dan Bahan..................................................................................... 22
B. Metode Penelitian ..................................................................................... 23C. Rancangan Percobaan................................................................................ 23D. Variabel Penelitian.....................................................................................
28E. Cara Pengukuran Variabel......................................................................... 29F. Tata Urutan Kerja ..................................................................................... 29G. Analisis Data ............................................................................................ 32H. Waktu dan Tempat Penelitian.................................................................... 33I. Jadwal Penelitian....................................................................................... 33
DAFTAR PUSTAKA........................................................................................... 34
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DAFTAR GAMBAR
Halaman
Gambar 1 Gambar skematis tentang respon tubuh terhadap stres................... 7
Gambar 2 Histologi tubulus seminiferus dan sel Leydig dengan pewarnaan HE. ................................................................................................ 10Gambar 3 Kerangka Teori ............................................................................. 19Gambar 4 Kerangka Konsep .......................................................................... 20
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DAFTAR LAMPIRAN
Halaman
Lampiran 1 Skema Alur Penelitian................................................................... 39Lampiran 2 Prosedur Randomisasi............................................ ...................... 40Lampiran 3 Prosedur Terminasi dan Dekapitasi............................................... 42Lampiran 4 Pembuatan Preparat Histologi........................................................ 43Lampiran 5 Gambar tangki model PSD............................................................ 47
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