cylophosphamide in neuropsychiatric sle

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CYLOPHOSPHAMIDE IN NEUROPSYCHIATRIC SLE

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Page 1: Cylophosphamide in Neuropsychiatric Sle

CYLOPHOSPHAMIDE IN NEUROPSYCHIATRIC SLE

Page 2: Cylophosphamide in Neuropsychiatric Sle

ALGORITMA PENATALAKSANAAN SLE

Perhimpunan Rheumatologi Indonesia, 2011. Diagnosis dan Pengelolaan Lupus Eritematosus Sistemik. Rekomendasi Perhimpunan Rheumatologi Indonesia

Page 3: Cylophosphamide in Neuropsychiatric Sle

Perhimpunan Rheumatologi Indonesia, 2011. Diagnosis dan Pengelolaan Lupus Eritematosus Sistemik. Rekomendasi Perhimpunan Rheumatologi Indonesia

Page 4: Cylophosphamide in Neuropsychiatric Sle

Perhimpunan Rheumatologi Indonesia, 2011. Diagnosis dan Pengelolaan Lupus Eritematosus Sistemik. Rekomendasi Perhimpunan Rheumatologi Indonesia

Page 5: Cylophosphamide in Neuropsychiatric Sle

Perhimpunan Rheumatologi Indonesia, 2011. Diagnosis dan Pengelolaan Lupus Eritematosus Sistemik. Rekomendasi Perhimpunan Rheumatologi Indonesia

Page 6: Cylophosphamide in Neuropsychiatric Sle

Perhimpunan Rheumatologi Indonesia, 2011. Diagnosis dan Pengelolaan Lupus Eritematosus Sistemik. Rekomendasi Perhimpunan Rheumatologi Indonesia

Page 7: Cylophosphamide in Neuropsychiatric Sle

– Cyclophosphamide given as monthly intravenous (500–1000mg/m2) doses for a six

month induction period followed by quarterly maintenance doses for a period of

two years

– Cyclophosphamide is a cytotoxic immunosuppressive treatment option with

documented therapeutic benefits in the management of severe NPSLE manifestations

unresponsive to other treatment modalities (nephritis and CNS manifestations)

Muscal, E & Brey, RL. 2011. Neurological Manifestations of Systemic Lupus Erythematosus in Children and Adults. NIH Public Access. Published in final edited form as:Neurol Clin. 2010 February

Page 8: Cylophosphamide in Neuropsychiatric Sle

DAPUS

• Muscal, E & Brey, RL. 2011. Neurological Manifestations of Systemic Lupus Erythematosus in Children and Adults. NIH Public Access. Published in final edited form as: Neurol Clin. 2010 February

• Perhimpunan Rheumatologi Indonesia, 2011. Diagnosis dan Pengelolaan Lupus Eritematosus Sistemik. Rekomendasi Perhimpunan Rheumatologi Indonesia