makalah drop kelompok 3

8/15/2019 Makalah Drop Kelompok 3

1/31


2/31

OH N-asetil-4-amino fenol

R66 M*6 C-HNO# %/'+ M*6 1511!

K6/,' M8'68 +,'* *6/'8 '/, 9$0: '

+,'* ;, '/, 1000: #$H9 NO2

E-* T/'


3/31

T '' '/6+' ;6--/ '.

/FI I! : 041

&'' *''' */,8+';, ''

*,', ''>'. D,,+,-,*', '/, ?'/'


4/31

';/' */6'*' -'+' '8 /+' +/''< -* '' %1

#.&. T2(33ta A(;t

A*,;'+ , +*,* /,6 ''' */, '+, (*/, +6;66

/', ' *' ,


5/31

'+,' &'/'+' ;',*>' +,'* ,;/,*' +/'6 '' *'/'

*68*,' ,;6*' -/. K2)tra I)53(a3

&86'' &'/'+' +,'* ,


6/31


7/31

1 9 ;'8,'


8/31

.. Baa) A(t38 Terp3'3

A+',- (' +/''?' ' +/6*+6/ *,,'.

.4. Be)t;( Se53aa) Terp3'3

", S


9/31

% 0 $.1 7.! 7.$5

&/,+68' D, (M'/+,')

• D, /'


10/31

1. L'/6+' '


11/31

• K'/6+' L'/6+ '' 5 ;'8,' ',/ 6*'/ '/6+ '' +'

(95:)

• I*/8', R, ' '' 86*'+ '

,'8 ,86'*' '''


12/31

002 B 012$ #

# B 01! M

# B 8'/' ''

01! B (N'2H&O4) (H2&O4=)

01! B 00! (H2&O4=

) (H2&O4=

)01! B 10! (H2&O4

=)

(H2&O4=) B

0,16

1,06

(H2&O4=) B 015M

(N'2H&O4) B 01! J 015

B 001 M

U+6* *'' +/;'/ 25

U+6* N'2H&O4

N'2H&O4 B Massa

Mr 1000

volume(mL)

001 M B Massa

141,96 1000

25

M'' N'2H&O4 B 0.04 8

U+6* N'H2&O4

N'H2&O4 B

Massa

Mr

1000

volume(mL)

015 M B Massa

119,98 1000

25

M'' N'H2&O4 B 0.44 8

U+6* *'' +/;'/ 300

U+6* N'2H&O4

N'2H&O4 B Massa

Mr 1000

volume(mL)

001 M B Massa

141,96 1000

300

M'' N'2H&O4 B 0.4 8

U+6* N'H2&O4

N'H2&O4 B Massa

Mr 1000

volume(mL)


13/31

015 M B Massa

119,98 1000

300

M'' N'H2&O4 B 5.3 8

Per3t;)*a) E6p3rat32) Date

&'/'+'


14/31

A+','8 * .

A6' ' 5

.. Ra)=a)*a) F2r7;'a3 Se53aa) Dr2p FORMULA % /%& 7'1

No

.

Nama Bahan Fungsi % Rentang

Pemakaian

%

dipakai

Jumlah

1" &'/'+' %'' A*+,- 0.75 8

" &/


15/31

6" N'H2&O4 D'/, K P 20 : 25 : 94!5 8

4" &E K 30: 1017 8

$" S/;,+ '+,'


16/31

6" S''/, N' &', 0075 J 0! : 01 : 003 8

'" E A886/ &?'/' '

&?'/' '


17/31

';, ,'6* ' '/6+ C,*' +/;+6* 8;68 '* 4.47 8 '* 9091 8 8' '?' '* 4!70 8 8' '?' '* !050 8 8' '?' '* 015 8 ' *+/ '6 '6*' '' ;+ ;/, +,*+ '

*'' *6/

SKEMA KER9A

#'


18/31

BAB !II

RANCANGAN E!ALUASI

4.%. Or*a)2'ept3

• W'/'

• R''

• %'6

4.#. Pe)etapa) pH

• A'+


19/31

. I,' '* 100 * '' ,*+/.

. &''8


20/31

BAB !

HASIL FORMULASI

%.%. F2r7;'a3 Terp3'3

FORMULA II /#& 7'1

N

o"

Nama

ahan

.un+si % /entan+

Pemakaian

%

,ipakai

itimba

n+

1" &'/'+' %'' A*+,- 1.25 8

" &/


21/31

"

11

"

&?'/' ,C'6 &?'/' . 1 ++

1

"

&/'' &/'' . 1 ++

13

"

A6'+ &;'?' A 25L

FORMULA terp3'3 II SCALE UP /$$ 7'1

N

o"

Nama

ahan

.un+si % /entan+

Pemakaian

%

,ipakai

itimba

n+

1" &'/'+' %'' A*+,- 15 8

" &/


22/31

4. %/'+ ",

&,*+/ *8 3333 8

&,*+/'6'+ 57!2 8

&,*+//


23/31

O;'+ ++ ''' ,'' ',/ ;/6'8

,',*' +6* ' ,'' /< ,'/''8 ;/6,'(0 J 1 +'6).

%'' >'8 '/6 '' '' ,'' /< ''' '8 ' +,'* '/6+ '' ',/ ++'' '8 ,86'*' ''' '*'/, N' '

/+'?;//> ;'8', '.

S,'' >'8 8'', ,


24/31

I. Ke37p;'a)

1. %+6* S,'' D/< N'*,*

2. K''/ %'' A*+,- &'/'+' 30 8G0! 3. O/8'

= R'' M',


25/31

DAFTAR PUSTAKA

1. A,. 2002. British Pharmacopoeia. L T S+'+,/> O--,.

2. 1979. Farmakope Indonesia, Edisi Ketiga.

3. 1995. Farmakope Indonesia, Edisi Keempat .

4. ',?'/' S6,+,' . 1995. Farmakologi dan Terapi, Edisi 4. "'*'/+' UI

&/.

5. ISFI. 2004. Informasi pesialite !"at Indonesia, Vol# $%.

!. R? R'> # . 200!. &and"ook of Pharmace'tical E(cipients, )th Ed#

W',8+ &'/'6+,'


26/31

LAMPIRAN

La7p3ra) %. Baa) Ta7+aa)

%. Pe'ar;t

%AHAN &EMERIAN KELARUTAN ADI KET. LAIN

A6' +,'+'

(FI III)

#',/' C/,

+,'*

;/?'/'+,'*

;/;'6+,'*

;/''

&/


27/31

%AHAN &EMERIAN KELARUTAN ADI KET. LAIN

S''/,

N'

(H&E

!42)

S/;6* *+' >8

;/?'/'


28/31


29/31

La7p3ra) #. Ke7aa)


30/31


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makalah drop kelompok 3

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