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    Trigger number five

    Ayu Kartika Sari

    405080161

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    Rhinitis Alergi

    Penyakit inflamasi yg disebabkan oleh

    reaksi alergi pd pasien atopi yg

    sebelumnya sudah tersensitisasi dgn

    alergen yg sama serta dilepaskannya

    suatu mediator kimia ketika terjadi

    paparan ulangan dgn alergen spesifik tsb.

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    Klasifikasi

    Saat ini digunakan ygberdasarkan klasifikasi WHO,

    ada 2 yaitu:a. Intermitten(kadang): gejala

    4hari/mgg ATAU > 4mgg

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    Manifestasi klinis

    Gejala khasnya adalah serangan bersin

    berulang

    Keluar ingus/rinore yg encer&banyak

    Hidung tersumbat

    Hidung dan mata gatal, kadang disertai

    banyak air mata

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    Komplikasi

    Polip hidung

    Otitis media efusi yg sedang residif,

    terutama pada anak2

    Sinusitis paranasal

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    Sinusitis

    Inflamasi mukosa sinus paranasal (sinus

    maksilaris, ethmoidalis, sphenoidalis,

    frontalis)

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    Etiologi

    Virus

    Rhinitis terutama Rhinitis alergi

    Rhinitis hormonal pd wanita hamil

    Polip hidung Kelainan anatomi seperti deviasi septum/ hipertrofikonka

    Infeksi tonsil

    Infeksi gigi Sumbatan KOM

    Kelainan imunologik

    Diskinesia silia

    Penyakit fibrosis kistik

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    Faktor predisposisi

    Lingkungan berpolusi

    Udara dingin dan kering

    Kebiasaan merokok

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    Manifestasi klinis

    Keluhan utama(akut)= HIDUNG TERSUMBAT

    Nyeri di daerah sinus

    Sakit kepala

    Hiposmia/anosmia

    Halitosis

    PND yg menyebabkan batuk dan sesak pdanak

    Sinusitis kronik tidak khas gejalanya.

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    Pemeriksaan

    Yg terpenting adalah menggunakan CT

    Scan

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    Penatalaksanaan

    Antibiotikuntuk sinusitis kronik

    Dekongestan oral dan topikal

    Antihistamin tidak rutin diberikan

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    Komplikasi

    Kelainan orbita

    Kelainan intrakranial

    Osteomilitis dan abses subperiostal Kelainan paru

    P k Eti l i G j l Kh P ik T t L k

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    Penyak

    it

    Etiologi Gejala Khas Pemeriksaan

    Penunjang

    Tata Laksana

    Deviasi

    Septum

    Trauma/

    ketidakseimb

    angan

    pertumbuhan.

    Sumbatan hidung yang

    menetap, Pada sisi deviasi

    terdapat konka hipotrofi,

    sedangkan sebelahnya terjadi

    konka hipertrofi akibat

    kompensasi.

    Pada pemeriksaan terlihat

    rongga hidung tidak sama

    besarnya antara kanan dan kiri.

    Penonjolan tulang/ rawan

    septum berbentuk krista/ spina/perlekatan

    - Tanpa gejala/

    keluhan sangat

    ringan tidak perlu

    koreksi.

    Keluhan nyata

    dirujuk untuk

    dilakukan reseksi

    submukosa atau

    septoplasti (reposisi

    septum).

    Polip

    Nasi

    Akibat reaksi

    hipersensitif

    atau reaksi

    atopik di

    dalam selaputmukosa

    hidung

    Sumbatan hidung yang

    menetap, makin lama makin

    berat.

    Hiposmia/ anosmia.

    Tampak massa putih keabu-abuan/ kuning kemarahan dalam

    kavum nasi.

    Polip bertangkai sehingga

    mudah digerakkan,

    konsistensinya lunak, tidak nyeri

    tekan, tidak mudah berdarah,

    dan tidak mengecil padapemakaian vasokonstriktor.

    Rontgen

    sinus.

    Pembuatan

    biakan hapus

    dari hidung(sebelum

    melakukan

    pengeluaran

    polip).

    Bila polip kecil,

    dapat diobati secara

    konservatif dengan

    kortikosteroid

    sistemik/ oral/ topikal.Bila polip besar,

    dilakukan ekstrasi

    polip dengan senar.

    Bila berulang dapat

    dirujuk untuk operasi

    etmoidektomi

    intranasal/ekstranasal.

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    Faringitis

    Peradangan akut membran mukosa faring

    dan struktur lain di sekitarnya

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    Gejala

    Nyeri tenggorokan

    Mual muntah

    Faring hiperemis

    Demam

    Nyeri tenggorokan

    Tonsil bengkak

    KGB leher anterior bengkak dan nyeri

    Uvula bengkak dan merah

    Petekie palatum mole

    Ruam skarlatina

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    Klasifikasi

    Saya hanya membahas faringitis akut

    karena kasus kita juga ttg faringitis

    akut(karena belum lebih dari 14 hari):

    >>Faringitis viral

    >>Faringitis bakterial

    >>Faringitis fungal

    J i P b b G j l t d T i

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    Jenis

    Faringitis

    Penyebab

    Tbanyak

    Gejala tanda Terapi

    F.VIRAL Rhinovirus -Demam,

    -rinorea,

    -mual,-nyeri tenggorok

    -susah mnelan

    Istirahat,

    minum yg cukup,

    kumur air hangat,analgetika&tablet hisap,

    AV metisoprinol pd infeksi

    herpes simpleks

    F.BAKTERIAL Strepto

    kokus beta

    hemolitikus

    group A

    -Nyeri kepala hebat,

    -muntah,

    -deman dgn suhu

    tinggi,

    -JARANG dgn BATUK

    antibiotik(penicilin),

    kostikosteroid,

    analgetika,

    kumur dgn air

    hangat/antiseptik

    F.FUNGAL Candida -nyeri tenggorok dannyeri mnelan

    -Mukosa faring

    hiperemis

    Nystatin,

    analgetika

    F.GONOREA Kontak

    orogenital -Sefalosporin generasi ke-3,

    Ceftriakson IM

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    Pneumonia

    Peradangan parenkim paru, distal dari

    bronkiolus terminalis yg mencakup

    bronkiolus respiratorius, dan alveoli serta

    menimbulkan konsolidasi jaringan parudan gangguan pertukaran gas setempat

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    Etiologi

    Berdasarkan kuman/ virus

    Berdasarkan lokalisasi

    Berdasarkan keadaan penderita

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    Klasifikasi

    Pneumonia di rumah perawatan(PN)

    Pneumonia yg terjadi >48jam setelah

    dirawat di RS tapi tidak sedang memakai

    ventilator

    Pneumonia Komunitas(PK)

    Pneumonia akibat infeksi di luar RS

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    Manifestasi Klinis

    Batuk dgn napas cepat

    Hidung melebar

    grunting Demam

    Ada crackles(ronki basah)

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    Faktor resiko PK

    Usia >65thn

    Adanya infeksi paru yg

    multilober/nekrotikans, pasca obstruksi

    atau aspirasi

    Penyakit penyerta(PPOK, DM,

    bronkiektasis, gagal ginjal, malnutrisi, dll)

    Tanda fisik yg memprediksi mortalitas,

    morbiditas dan komplikasi

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    Pemeriksaan

    Gambaran radiologis berupa pneumonia

    alveolar dgn gambaran air bronkogram

    Distribusi infiltrat pd segmen apikal lobus

    bawah atau inferior lobus

    Bentuk lesi berupa kavitasi dgn air fluid

    level sugestif

    Pembentukan kista

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    Leukositosis

    Titer antibodi terhadap virus, legionella,

    dan mikoplasmatiter tinggi/ kenaikan

    titer 4x

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    Penatalaksanaan

    Bacterial. Doctors usually treat bacterial pneumonia withantibiotics. Stopping medication too soon may cause yourpneumonia to return. It also helps create strains of bacteriathat are resistant to antibiotics.

    Viral. Antibiotics aren't effective against most viral forms of

    pneumonia. And although a few viral pneumonias may betreated with antiviral medications, the recommendedtreatment generally is rest and plenty of fluids.

    Mycoplasma. Mycoplasma pneumonias are treated withantibiotics. Many cases of mycoplasma pneumonia goundiagnosed and untreated. The signs and symptoms mimic

    those of a bad chest cold, so some people never seekmedical attention. The symptoms generally go away on theirown.

    Fungal. If your pneumonia is caused by a fungus, you'll likelybe treated with antifungal medication.

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    Komplikasi

    Bacteria in your bloodstream. Pneumonia can be life-threatening wheninflammation from the disease fills the air sacs in your lungs and interfereswith your ability to breathe. In some cases the infection may invade yourbloodstream (bacteremia). It can then spread quickly to other organs.

    Fluid accumulation and infection around your lungs. Sometimes fluidaccumulates between the thin, transparent membrane (pleura) coveringyour lungs and the membrane that lines the inner surface of your chest wall a condition known as pleural effusion. Normally, the pleurae are smooth,allowing your lungs to slide easily along your chest wall when you breathe inand out. But when the pleurae around your lungs become inflamed(pleurisy) often as a result of pneumonia fluid can accumulate andmay become infected (empyema).

    Lung abscess. A cavity containing pus (abscess) that forms within the areaaffected by pneumonia is another potential complication.

    Acute respiratory distress syndrome (ARDS). The pneumonia involvesmost areas of both lungs, making breathing difficult and depriving your bodyof oxygen. Underlying lung disease of any kind, but especially COPD,makes you more susceptible to ARDS.

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    TBC

    Tuberkulosis (TBC atau TB) adalah suatu

    penyakit infeksi yang disebabkan oleh

    bakteri Mikobakterium tuberkulosa. Bakteri

    ini merupakan bakteri basil yang sangatkuat sehingga memerlukan waktu lama

    untuk mengobatinya. Bakteri ini lebih

    sering menginfeksi organ paru-parudibandingkan bagian lain tubuh manusia.

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    Epidemiologi

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    Etiologi

    Mycobacterium tuberculosis, sejenis

    kuman berbentuk batang dgn panjang 1-

    4/um dan tebal 0,3-0,6/um

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    Manfes

    Batuk terus-menerus selama 3minggu/ lebih Sakit di dada

    Batuk berdarah atau berdahak (lendir daribagian dalam paru2)

    Letih/ mudah capai

    BB

    Kehilangan nafsu makan

    Demam Menggigil

    Berkeringat di malam hari

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    Pemeriksaan Penunjang

    *A small reaction (5 mm of hard swelling at the site) is considered to be positive inpeople:-Who have HIV-Who are taking steroid therapy-Who have been in close contact with a person who has active tuberculosis*Larger reactions (greater than or equal to 10 mm) are considered positive in:-People with diabetes or kidney failure-Health care workers*In people with no known risks for tuberculosis, a positive reaction requires 15 mm

    or more of hard swelling at the site

    Purified ProteinDerivative(PPD) adalah

    sebuah antigen yg

    disuntikan secara

    intradermal di bagian

    volar lengan bawah.

    Setelah 48-72 jam,bagian yg disuntik akan

    dievaluasi oleh dokter.

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    P t l k IMUNISASI KIE

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    Penatalaksanaan IMUNISASI,KIE,

    FARMAKO

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    Tumor paru

    Tipe histologi:

    1. Small cell ---------------------20%

    2. Squamus carcinoma ---------30%.3. Adenokarsinoma ------------40%

    4. Large cell carcinoma --------10%.

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    Small cell carcinoma :

    - Bersifat agresif, mudah bermetastase.

    - Respons terhadap kemoterapi cukup baik.

    - Mikroskopik:* Kelompokan sel hiperkromatik dengan inti

    moulding (secara sitologi).

    * Sel spindle,inti gelap.

    * Tersusun berkelompok (sheet, cord).

    - Sel tumbuh dari sel neuroendokrine

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    Adenokarsinoma. :

    - Sering pada wanita.

    - Non smokers.

    - 2/3 dijumpai di daerah perifer paru.

    - Ada 2 jenis:

    1. Sel tumor tersusun bentuk acini

    dengan jaringan ikat stroma.

    2. Sel tumor tersusun sepanjangdinding alveolus ( bronchi alveolar

    carcinoma).

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    Squamus cell carcinoma :

    Hubungan dekat dengan merokok

    Tumbuh dari bronchi besar dengan epitel

    yang mengalami metaplasi displasi

    Sering ada perdarahan dan nekrosis

    Berdiferensiasi baik jelek

    Metastase ke kelenjar Hilus

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    Large cell carcinoma :

    - Tumbuh di sentral.

    - Sel besar.- Etiologi :

    * Rokok : - aktif

    -pasifkarena adanya benzypyrene

    dan nitrosamine.

    * Polusi : industri, asbes, radiasi,

    bahan metal.

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    Bronchiechtasis

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    SALURAN NAPAS BAWAH

    BAGIAN

    OBSTRUKSI

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    Bronkiolitis

    swelling and mucus buildup in the smallestair passages in the lungs (bronchioles),

    usually due to a viral infection.

    usually affects children under the age of 2,with a peak age of 3 - 6 months

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    Etiologi

    Respiratory syncytial virus (RSV) is the

    most common cause.

    Other viruses that can cause bronchiolitis

    include:

    Adenovirus

    Influenza

    Parainfluenza

    http://www.nlm.nih.gov/medlineplus/ency/article/001564.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/000080.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/001370.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/001370.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/000080.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/001564.htm
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    Manifestasi Klinis

    Bluish skin due to lack of oxygen (cyanosis) Cough, wheezing, shortness of breath, or

    difficulty breathing

    Fever

    Intercostal retractions

    Nasal flaring in infants

    Rapid breathing (tachypnea)

    Decreased blood oxygen Wheezing and crackling sounds heard

    through stethoscope exam of chest

    http://www.nlm.nih.gov/medlineplus/ency/article/003215.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/003070.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/003070.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/003215.htm
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    Penatalaksanaan

    Sometimes, no treatment is necessary. Supportive therapy can include:

    -Chest clapping

    -Drinking enough fluids. Breast milk or formula are okay for childrenyounger than 12 months. Offer warm lemonade or apple juice if yourchild is over 4 months.

    -Breathing moist (wet) air helps loosen the sticky mucus that may bechoking your child. You can use a humidifier to moisten the air yourchild is breathing. Follow the directions that come with thehumidifier.

    -Getting plenty of rest

    -Do not let anyone smoke in the house, car, or anywhere near your

    child.*Antibiotics are not effective against viral infections. Mostmedications have little effect on bronchiolitis. Children in the hospitalmay need oxygen therapy and fluids given through a vein (IV) tostay hydrated.

    -In extremely ill children, antiviral medications (such as ribavirin) are

    used in rare cases.

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    Komplikasi

    Airway disease, including asthma, later in

    life

    Respiratory failure

    Additional infection, such as pneumonia

    http://www.nlm.nih.gov/medlineplus/ency/article/000145.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/000145.htm
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    Faktor Resiko

    Exposure to cigarette smoke

    Age younger than 6 months old

    Living in crowded conditions

    Lack of breast-feeding

    Prematurity (being born before 37 weeks

    gestation)

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    COPD

    Chronic obstructive pulmonary disease (COPD)

    refers to chronic lung disorders that result in

    blocked air flow in the lungs. The two main

    COPD disorders are emphysema and chronic

    bronchitis, the most common causes of

    respiratory failure.

    Emphysema occurs when the walls between

    the lung's air sacs become weakened and

    collapse. Damage from COPD is usually

    permanent and irreversible.

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    Chronic bronchitis is most frequently causedby long term irritation of the bronchial tubes.

    Bronchitis is considered "chronic" if symptoms

    continue for three months or longer. Bronchitis

    caused by allergies can also be classified as

    chronic bronchitis. Chronic bronchitis is caused

    most often by exposure to airborne pollutantssuch as cigarette smoke, excessive dust in the

    air, or chemicals. The bronchial lining becomes

    inflamed and the constant exposure to such

    pollutants begins to cause damage in the

    bronchioles (the smaller airways in the lungs).

    Symptoms of chronic bronchitis includeshortness of breath or wheezing, chest pain,

    and chronic productive cough.

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    Asthma

    Asthma is a lung disease that makes itharder to move air in and out of yourlungs. There are three things that you

    should know about asthma: Asthma is chronic. In other words, you live

    with it every day.

    It can be serious even life threatening.

    There is no cure for asthma, but it can bemanaged so you live a normal, healthy life.

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    Etiology

    Genetics. Asthma tends to runs in families. Genetics plays animportant role in causing asthma. If your mom or dad have asthma,then you are more likely to have asthma too.

    Allergies. Some people are more likely to develop allergies thanothers, especially if your mom or dad had allergies. Certain allergiesare linked to people who get asthma.

    Respiratory Infections. As the lungs develop in infancy and earlychildhood, certain respiratory infections have been shown to causeinflammation and damage the lung tissue. The damage that iscaused in infancy or early childhood can impact lung function long-term.

    Environment. Contact with allergens, certain irritants, or exposure to

    viral infections as an infant or in early childhood when the immunesystem in developing have been linked to developing asthma.

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    Predisposition factors

    Respiratory Infections. such as a cold, flu, or sinus infection, are the mostcommon cause of asthma symptoms leading to an asthma flare-up

    Allergens. Allergens, such as pollen, mold, dust, dust mites, cockroaches,animal droppings, and dander from animals with fur or feathers

    Irritants. include perfumes, cleaning fluids, cigarette smoke, air pollution,wood smoke and kerosene heaters.

    Exercise. They may produce more mucus leading to asthma symptoms. Emotions. Crying, yelling or even laughing may cause asthmasymptoms. Stress, both personal and work-related, can be a major trigger.

    Chemicals. Certain chemicals cause severe asthma symptoms in peoplewith asthma. Seasonal/Time Triggers. Some people with asthmaexperience more problems with symptoms at certain times of the day(during sleeping time when airways tend to close to close some), certain

    times of the month (hormonal changes in women during pregnancy ormenstruation), or certain times of the year (when pollen levels are high suchas in the fall and the spring).

    Smoking. Tobacco smoke irritates the airways.

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    Manifestasi klinis

    Wheezing. You may notice a wheezing soundwhen you breathe. Sometimes this happens onlywhen you exercise or have a cold.

    Frequent Cough. This may be more common at

    night. You may or may not cough up mucus. Shortness of Breath. This is the feeling you can't

    get enough air into your lungs. It may occur onlyonce in a while, or often.

    Chest Tightness. Your chest may feel tight,especially during cold weather or exercise. Thiscan also be the first sign of a flare-up.

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    PATOFISIOLOGI

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    Pencegahan

    Get a flu shot. Protect your infants and toddlers

    from getting the flu. Children 6 months of age

    and older are one of the targeted group to

    receive the influenza vaccine. If you care for achild less than 6 months of age, it important for

    you to get a flu shot to help protect them from

    getting sick.

    Avoid exposure to tobacco smoke. If you or afamily member smokes, don't smoke around

    your child. Make a plan to quit

    http://flucliniclocator.org/http://flucliniclocator.org/
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    Farmako asthma

    Beta adrenoceptor agonist

    Theophyline

    Corticosteroids

    Chromolyn dan Nedocromil

    Leukotrien pathway inhibitor

    Anti Ig-E monoclonal antibody

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    PERBEDAAN PPOK DAN ASMA

    PPOK Asma

    Umur mula Dekade ke 6 Variasipenyakit paling cepat awal 40

    Peran Sangat berperan - kurang berperanmerokok - dpt memperberat

    Reversibiliti obstruksi kronik - obs. episodikobstruksi dan menetap - VEP-1 normal

    waktu remisiVEP-1 menetap - VEP-1 membaikdgn bronkodilator dgn bronkodilatorsedikit perbaikan

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    PPOK Asma

    Perjalanan progresif episodikpenyakit lambat

    Riwayat jarang sering

    alergi

    Kapasiti menurun normaldifusi

    Hipoksemia kronik jarang

    Spirometri dapat membaik perbaikan nyatadgn bronkodilator dgn bronkodilator