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    The Literature Search Process:

    Guidance for NHS ResearchersDeveloped by Thames Valley & Wessex Healthcare Librarians*

    Version: 5.0 Issue date: August 2013 Review date: January 2015

    Introduction

    This document was deveo!ed in !artnershi! with the Thames Vaey Research "#eveo!ment $etwor% and is maintained &y heathcare i&rarians in Thames Vaey "'essse(. Its aim is to su!!ort $)* researchers in carrying out e+ective iterature searches.This wi he! ensure that research is not du!icated and that iterature searches retrieve the&est avaia&e evidence.

    This document !rovides guidance ,or the ,oowing %ey ste!s:

    1 !anning a iterature search

    2 identi,ying %ey sources o, in,ormation

    3 guidance in carrying out an e+ective iterature search

    4 documenting the search !rocess

    *tructured guidance and a chec%ist coumn are !rovided ,or each section so that

    researchers can -uic%y identi,y and tic% o+ the necessary eements. ou are strongyencouraged to contact your oca heathcare i&rarian at the start o, your research !ro/ectthey wi &e a&e to o+er !ro,essiona advice and su!!ort. To nd your oca i&rary !easevisit htt!:www.hisd.org

    This wor% &uids on !revious internationa wor% in this area which is credited in the&i&iogra!hy.

    This is a wor%ing document that wi evove to meet the needs o, the oca $)* researchcommunity there,ore your ,eed&ac% is o, the utmost im!ortance. 4ease contact us withcomments and suggestions.

    *arah ewis 6inica 7utreach i&rarian 8uc%inghamshire )eathcare $)* TrustTe: 0129 ;10;2 emai: *arah.ewisiham 8everey )i(on ?ran amusse Ae( 6oey @arena *ce!ans%a Jo ?a&ing 6ive @is%in 8ar&ara@oye Ji 8uc%and Jo aing i 6aow. Than%s aso to Rosaind @c$ay ,rom @anchester )eath and *ocia6are Trust.

    With grateful acknowledgements to: Carol Lefvebre (UK Cochrane Centre), Claire CheongLeen, teve !airman,

    !unmi !a"emisin, #eo$ !leet, %nnette &ackett, 'essica homas, al rinder and delegates of the *nd

    hames alle+

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    -. /etwork Worksho0, 12ford, 34th

    'ul+ *5567

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    CONTENTS

    8age

    SearchPlanning Form 3

    Guidance Notes for Use with Search Planning Form: USING PICOAS AN EA!P"E B

    Guidance Notes for Use with Search Planning Form: OT#E$F$A!E%O$&S 5

    "iterature Search Protocols

    *ection 1. Resource chec%ist

    eve 1: 6ore resources

    aC @inimum core resources

    &C 7ther core resources

    eve 2: Recommended resources D

    eve 3: Additiona resources D

    *ection 2. *earch strategy chec%ist

    aC Range o, search terms ;

    &C #ata&ase su&/ect headings ;

    cC *earch techni-ues 9

    *ection 3. *earch documentation chec%ist 10

    A''endices ( see se'arate document

    1. >uide to sources o, in,ormation i

    2. Additiona su&/ect s!ecic data&ases (vi

    3. 8i&iogra!hy (viii

    2

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    Search Planning Form

    Ese this ,orm to identi,ycari,y the %ey conce!ts and the sco!e o, your researchto!ic.

    ee the guidance notes for a worked e2am0le

    #ate search started: FFFFFFFFFFFFFFFFF #ate search com!eted:FFFFFFFFFFFFFFFFFFFFF

    1.)our $esearch To'ic

    2. *rea+ down ,our to'ic into +e, conce'ts or categories to formulate a clear clinical-uestion

    (f +our to0ic does not easil+ ;t into these categories, see the guidance notes on 0age 4)

    Patient.Po'ulationand.or

    Inter/ention/E0'osure

    Com'arison.Control Outcome

    Pro1lem

    Alternati/e %ords ( ist &eow in the a!!ro!riate coumn

    3.)our $esearch 2uestion

    4. Search limits*tudy ty!e: 4u&ication date:

    Age range: anguage:

    7ther:

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    Guidance notes for use with Search Planning Form: USING PICO ASAN EA!P"E

    1.)our $esearch To'ic ( &rieGy descri&e in your own words the %ey as!ects o, your researchto!ic

    2.*rea+ down ,our to'ic into +e, conce'ts or categories to formulate a clear clinical-uestion

    The 4I67 mode HRichardson 1995C is an evidence&ased mode ,or ,ormuating a cinica-uestion using the headings Patient!o!uation andor !ro&emIntervention3 Com!arison andOutcome. 8y dividing your to!ic into these orsimiar categories you wi aso &e doing thegroundwor% ,or deveo!ing a search strategy. f the 8C1 headings do noteasil+ ;t +our researchto0ic, 0lease see 0age 4 for alternatives7

    1 Patient.Po'ulation.Pro1lem any characteristics that dene your !atient or!o!uation e.g. target cinicacondition coe(isting condition ethnicity age grou!

    2 Inter/ention.E0'osure what you want to do with the !atient!o!uation!ro&eme.g. ,orm o, treatmentdiagnostic test education !rogramme ty!e o, service deivery.This can aso incude any e(!osures He.g. as&estosC or ,actors inGuencing !rognosis

    3 Com'arison.Control Hi, a!!ica&eC( aternativeHsC to main intervention e.g. !ace&o

    4 Outcomes any outcomes or e+ects reating to the intervention e.g. !reventionside e+ects mor&idity-uaity o, i,e coste+ectiveness

    The 4I67 headings shown in the e(am!e do not have to &e a!!ied rigidy and there are anum&er o, variations e.g.

    1 PICOT 4 Patient Intervention Com!arison Outcome Time ?rame H?ineout7verhotand Johnson 2005C

    2 PICOCs Po!uation Interventions Com!arators Outcomes Conte(t Studydesign H4etticrew andRo&erts 2005C

    'hen ing in each category consider any synonyms aternative %eywords di+erents!eings acronyms etc. to incude in your search strategy see guidance notes on 0age uideines sitese.g. $)* Lvidence

    $I6L

    ! 'e&sites o, reevant associations &odies5

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    earched />% Unable to

    8 $esource Chec+list !continued" "E9E" 6: $ECO!!EN5E5 $ESOU$CES access

    "e/el 6: $ecommended resources

    Case re'orts*ome o, these resources may he! to ocateun!u&ished

    iterature incuding theses " con,erence!roceedings. ! 6ases#ata&ase

    They are use,u i, you need a greater eve o,condence

    Conference 'roceedings

    ! PeT76=that you are not du!icating other research.)owever

    access to some o, these sources may &e

    imited. 5issertations and ThesesThere may aso &e other su&/ect s!ecicdata&ases o,

    ! #ART Luro!e LThesis 4orta

    !interest. #issertation and Theses #ata&ase =

    = Resources mar%ed with a = are not avaia&ethrough

    ! LTh7*

    ! Inde( to Theses=$)* Athens or ,ree on the Internet. Access isthrough

    su&scri!tion ony &ut may &e accessi&e at youroca ! $etwor%ed #igita i&rary o, Theses and #issertationsheath or academic i&rary.

    5rug Information

    ! #rug and Thera!eutics 8uetin =

    ! @icromede( =

    ! @edicines In,ormation

    ! 4harmaceutica and device manu,acturers

    Gre, "iterature

    ! 7!en >rey

    "i1rar, catalogues

    Other resources

    ! $I)R Journas i&rary

    ! QI44 HQuaity Innovation 4roductivity and 4reventionC

    ! EO #uets H#ata&ase o, Encertainties a&out the L+ectso,

    TreatmentsC

    Su1;ect S'eci

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    ! 8ioogica A&stracts=

    ! LRI6 HLducation Resources In,ormation 6enterC

    "

    (hames )alle+ - Wesse2 Literature earch 8rotocols v7475, %ugust*539

    $ECO!!EN5E5 $ESOU$CES CONTINUE5 earched />%Unableto

    ! >o&a )eath =

    ! )eath 8usiness Lite

    ! @aternity and In,ant 6are=

    ! *ciVerse *co!us=

    ! *ocia 4oicy and 4ractice=

    ! *cience 6itation Inde( L(!anded=

    ! *ocia *ciences 6itation Inde( =

    ! T7$LT HTo(icoogyC

    ! 'ord )eath 7rganisation Regiona #ata&ases

    $esearch in 'rogress . s'ecialist health researchresources

    ! 6inicaTrias.gov

    ! metaRegister o, 6ontroed Trias HmR6TC

    ! $I)R 6inica Research $etwor% 4ort,oio #ata&ase

    !

    4ros!ero HInternationa 4ros!ective Register o,*ystematicReviewsC

    %e1 search engines e.g. >ooge >ooge *choar

    "e/el =: Additional resources "E9E" = : A55ITIONA" SEA$C# !ET#O5SThese resources wi ,urther increase the

    !

    6ontacting centres o, e(ceence and e(!erts in theedcom!rehensiveness o, your search. $.8. you may

    want to

    ! Lmai onine discussion grou!sweigh u! the i%eihood o, ocating signicantynewin,ormation &e,ore investing the time needed toe(!ore ! )and searching o, %ey /ournasthese methods.

    ! 6itation trac%ing re,erence ist chec%ing

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    #

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    6 Search Strateg, Chec+list

    8e,ore carrying out your search you wi need to identi,y your research -uestion and !an your search strategy. ou wi areadyhave identied your research -uestion and &ro%en it down into di+erent conce!ts when com!eting the *earch 4anning ?orm.

    This section wi he! you identi,y a range o, %eywords reevant to your research -uestion. It incudes essentia searchtechni-ues that shoud &e used wherever !ossi&e to carry out an e+ective search o, your chosen sources. 6ontact youroca heathcare i&rarian ,or ,urther advice training

    Used .Identi

    =mergenc+ oomeach data&ase and review your search termsHand i,

    ! #i+erences in s!eings e.g.anaemia > anemianecessary your research -uestion and itssco!eC

    ! 7d and new terminoogy e.g.mongolism > down s+ndrome&e,ore carrying out your na searches.

    ! 8rand and generic names e.g.coumadin > warfarin

    ! ay and medica terminoogy e.g.stroke > cerebrovascular accident

    *u&/ect headings are used to inde( thecontent o, 1 5ata1ase su1;ect headingsmost &i&iogra!hic data&ases H@L#I$LL@8A*Letc.C L(am!e: heart attac% is inde(edunder

    ! Identi,y a!!ro!riate su&/ect headings ,or each data&ase used@76AR#IA I$?AR6TI7$The su&/ect headings ist used in @L#I$Lis caed

    @e*) H@edica *u&/ect )eadingsC. ! 6hec% coverage sco!e and denition o, each su&/ect headingoo% ,or the @e*) or Thesaurus o!tions toidenti,y

    $8: *ometimes su&/ect headings are not dened as you might e(!ect e.g.the @e*) heading

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    the most a!!ro!riate su&/ect heading ,orthe

    S*ER>LR is used to inde( materia on the disci!ine o, surgery not surgica!rocedures Hthis

    %eyword you have entered. is inde(ed under *ER>I6A 4R76L#ERL* 74LRATIVLC.6orrect use o, su&/ect headings im!rovestheaccuracy o, your resuts and is essentia toan

    e+ective search. H*ee section 2cC

    See ne0t 'age for continued guidancenotes.

    $

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    6 SearchStrateg,Chec+list

    !continued"

    GuidanceNotes@ost o,

    these searchtechni-uesare ,or usewith&i&iogra!hicdata&asese.g.@L#I$L. I,a !articuarsearchtechni-ue isnota!!ica&etic% the &o(in the $Acoumn.

    Truncation

    Truncation

    sym&osHaso %nownas widcardsCare used tore!ace anynum&er o,charactersat the end o,the worde7g7behavio@ willalso ;ndbehaviors,behaviourbehavioural

    etc7Theactuasym&osused varyde!endingon thedata&aseservice!rovider.As adata&asecan &emadeavaia&ethrough

    more thanoneservice!rovideryou wineed tochec% thedata&asehe!section tond outwhichsym&o touse. Themostcommonsym&o = isused &y4u&medand the$)*Lvidence)eathcare#ata&ases. 7therdata&asesor service!rovidersmay use Uor M

    Com1iningsearch

    results

    Ese AN5to com&inetwo di+erent conce!tse.g. dia&etes A$#insuin

    HA$# wi narrow yoursearch yourresuts must incudeA your statedconce!tsC

    Ese O$to search ,orsimiar conce!ts e.g.retina 7R eye

    H7R wi widen yoursearch yourresuts wi incudea @I$I@E@ 7? 7$Lo, your namedconce!tsC

    U'dating searches:this !rocess can havemany !it,as. I, youhave a !re!re!aredsearch that you wish tou!date or rerun at aater date !easecontact your ocaheathcare i&rarian.

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    c Search techni-ues! 6arry out se!arate searches ,or each individua conce!t and thencom&ine at a

    ater stage

    =2am0le search

    1. dia&etic 7R dia&etes

    2. retina 7R eye3. 1 A$# 2

    ! Ese a com&ination o, te(t words H,ree te(tC and su&/ect headingsearches

    ! Ese a!!ro!riate truncation ,or te(t word searches where a!!ica&e

    e.g. nurs= tond nurse, nurses, nursing

    !

    L(!odeW Hi.e. e(!andC data&ase su&/ect headings where a!!ro!riateto incudenarrower terms

    ! Avoid restricting data&ase su&/ect heading searches using the descri0torsA

    or subheadingreevant materiaC

    ! Ese A$# 7R a!!ro!riatey to com&ine resuts o, se!arate searches

    ! Avoid imiting your search to Lngish anguage Hto he! !revent &iasC

    ! 'hen searching we&sites or other eectronic sources use thAdvancedW search

    o!tion where avaia&e! I, a!!ro!riate use search ters H!re!re!ared search strateidenti,y

    !articuar ty!es o, research studies e.g. randomised contr*ources o,

    search ters incude:

    14

    u&@ed

    Ws6inicaQu

    eries

    2 6ochrane i&rary)and&oo%

    3 InterTA*6In,ormation*!eciaistsX*u&>rou!*earch?iterResource

    4 6ontactyour ocaheathcarei&rarian ,or

    advice.

    2 Ese the 4u&@edreated articesW,unction and istso, re,erences in6I$A)

    3 6hec% there,erences citedin any research other reevantmateriaretrieved

    %

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    = Search 5ocumentation Chec+list

    Guidance Notes

    This chec%ist outines the minimum re-uired to document thesearch !rocess carried out in su!!ort o, any research !ro!osa.

    A eements must &e ceary documented ,or eachresource searched.

    *ee the Guide to Sources of Informationin the A!!endices,or detais o, each resource isted in the chec%ist.

    Please ensure ,our research 'ro'osal includes:

    a Clearl, statedresearch -uestion

    1 E0'lanation ofthe sco'e of theresearch -uestion

    c For data1asesearches3s'eci

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    '

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    NOTES