makalah farmako calcium antagonis

7/26/2019 Makalah Farmako Calcium Antagonis

1/13

TUGAS FARMAKOLOGI KARDIOVASKULER

CALCIUM ANTAGONIS

Nama: Dheya Membutu Olmus (1!"!1!!#$%

S&' S N ) Kusum* (1!"!1!!#%

A+,es G M V G Te-e (1!"!1!!#.%

Rahmat Nu&-a, Nu+&aha (1!"!1!!#/%

A0a&ella A all* (1!"!1!!#2%

Desy R's,a,t' Lambe (1!"!1!!#"%

A&ah Mu&,' A Ullu (1!"!1!!#3%

Gust',a M M**y (1!"!1!!!%

4*&5a, I D'&a T*me (1!"!1!!1%

Semeste&: (Em6at%

FAKULTAS KEDOKTERAN

UNIVERSITAS NUSA CENDANA

$!1.7$!1/


2/13

Cal8'um A,ta+*,'st

A. Definisi dan Tujuan

Cals'um a,ta+*,'s a5alah *bat hete&*+e, 5a, +*l*,+a, *bat 6e,u&u, te9a,a, 5a&ah atau a,t'

h'6e&te,s' ya,+ be&9e&a 5e,+a, 8a&a me,+hambat 6emasu9a,'*, 9als'um 9e 5alam sel *t*t

;as9ula& 6e&'


3/13

m'*9a&5'um 5a&' 6a5a ;e&a6am'l T'5a9 se6e&t' ;e&a6'm'l=,'bl*89e&Ebl*89e&Ehat'a, b'la 5'+u,a9a, be&sama beta>bl*89e&

C. Farmakodinamika

Me9a,'sme Ke&a

Salu&a, 9als'um t'6e L be&6',tu ;*ltase me&u6a9a, t'6e 5*m',a, 5' *t*t a,tu,+ 5a,

*t*t 6*l*s se&ta 5'9e,al me,+a,5u,+ bebe&a6a &ese6t*& *bat Salu&a, ',' te&5'&' 5a&' subu,'t

1 (subu,'t 6embe,tu9 6*&'= leb'h besa&%= $= B= = 5a, Telah 5'9etahu' a5a,ya em6at

;a&'a, subu,'t 1 N'


4/13

Obat be9e&a 5a&' s's' 5alam memb&a, 5a, be&'9ata, se8a&a leb'h e*bat ',' leb'h &e,5ah 9a&e,a salu&a, 5' sel>sel ',' a&a,+ 5alam 9ea5aa,

te&bu9a 5a, ',a9t'*bat ',' teta6' t'5a9 te&lalu ,yata l*9 5a6at 5'6ul'h9a, se8a&a

6a&s'al 5e,+a, me,',+9at9a, 9*,se,t&as' 9als'um= mes9'6u, 9a5a& 9als'um ya,+ 5'6e&lu9a,

t'5a9 mu5ah 5'8a6a' 6a5a 6as'e, l*9 u+a 5a6at se8a&a 6a&s'al 5'6ul'h9a, 5e,+a,

6embe&'a, *bat>*bat ya,+ me,',+9at9a, *bat ',' Salu&a, 9als'um 5' *t*t 6*l*s ;as9ula& 5'hambat *leh

;e&a6am'l= seh',++a ;as*5'latas' ya,+ 5't'mbul9a, *leh *bat ',' Salu&a, ,at&'um se&ta

salu&a, 9als'um 5'hambat *leh be6&'5'l= suatu *bat a,t'a&'tm'a ya,+ t'5a9 la+' 5'+u,a9a,

Esel ',' melemas *leh

6e,+hambat salu&a, 9als'um Ot*t 6*l*s ;as9ula& tam6a9,ya a5alah ya,+ 6al',+ se,s't'

;a&'a, +abu,+a, 5alam st&u9tu& subu,'t salu&a, 1 tam6a9,ya me,a5' 6e,yebab 6e&be5aa,

te&sebut


5/13

$ Ot*t a,tu,+ > Ot*t a,tu,+ sa,+at be&+a,tu,+ 6a5a ',lambat= atau 5e6e,5e,

9als'um>mu,+9', be&9u&a,+ atau te&he,t' *eh semua 6e,+hambat salu&a, 9als'um

)e,++abu,+a, e9s'tas'>9*,t&a9s' 5' semua sel a,tu,+ meme&lu9a, ', *bat ',' me,+u&a,+' 9*,t&a9t'l'tas a,tu,+ se8a&a 5e6e,5e,>5*s's )a5a seba+'a, 9asus=

8u&ah a,tu,+ u+a 5a6at be&9u&a,+ )e,+u&a,+a, 9*,t&a9s'

5a, t'5a9 meme&lu9a, ba,ya9 ',a&te&' 6a5a st&*9e ebe&a6a bu9t' me,yata9a, bah-a 6e,+hambat salu&a, 9als'um

u+a 5a6at me,+u&a,+' 9e&usa9a, *ta9 setelah st&*9e t&*mb*emb*l'

. E


6/13

Ve&a6am'l telah 5'bu9t'9a, me,+hambat +l'9*6&*te', ) ya,+ be&6e&a, 5alam

6e,+a,+9uta, ba,ya9 *bat 9elua& 5a&' sel 9a,9e& 5a, sel la', )e,+hambat 9als'um la',

tam6a9,ya mem'l'9' eL= 5'ba+' me,a5' $ +*l*,+a, besa&= a,ta+*,'s 9als'um ,*,>5'h'5&*6'&'5', 5a,

a,ta+*,'s 9als'um 5'h'5&*6'&'5', G*l*,+a, 5'h'5&*6'&'5', be9e&a 6a5a a&te&' seh',++a 5a6at

be&la', : 6&e,'lam',= 6e&he9s'l',= 5ll

G*l*,+a, 1= $ 5a, # me,+hambat se8a&a sele9t'< 9a,al Ca$H (3!>1!!%= se5a,+9a,

9el*m6*9 la',,ya me,+hambat 9a,al Ca0H (.!>2!% 5a, 9a,al NaJ U&a'a, sela,ut,ya

5'batas' 6a5a 9e># 6&*t*t'6e CC= ya9,' ,'e,'s se5'aa, :

1 A5alat

$ A5alat CC

# A


7/13

1$ Ca&5e,e SR

1# D'lta0em

1 D'lat&ate

1. D'la8*&

1/ D'lta0em CD12 D'lt'a

1" Is*6t',

13 N'8a&5'6',e

$! N'1 ha&' )a5a 6as'e, la,s'a atau +a,++ua,


8/13

N'8a&5'6',e Cl In: l'hat 6a5a 5*s's Ds: I,/ m8+79+7m,tKm:Dus= 1! 5us 1 ;'al

1! mL ', 1 m+7mL

F. 'ndikasi dan Efek Samping

+. A,%OD'P'&

'ndikasi-

h'6e&te,s'= 6&*


9/13

mu9a me&ah= sa9't 9e6ala= 6al6'tas'= 6us',+=fatigue= e5ema 9a9'= &uam 9ul't 5a, +atal=

h'6e&6las'a= 5emam= 'm6*te,

1. 'S/AD'P'&

'ndikasi-

h'6e&te,s'

Efek Samping-

sa9't 9e6ala= -aah meme&ah= 6us',+= ta9'9a&5' 5a, 6al6'tas'= e5ema 6e&'


10/13

'leus 6a&al't'9= h'6*9sem'a= e5ema 6a&u= 5's6,ea= ,ye&' a,+',a= t&*mb*s't*6e,'a= +a,++ua,


11/13

Ke5ua,ya 5a6at me,',+9at9a, 9e9uata, 8ha,,el bl*89',+ 5a&' a,t'>hy6e&te,s' ya,+ 5a6at

membe&'9a, 6e,+a&uh ya,+ bu&u9 a&us 5'+u,a9a, 5e,+a, hat'>hat' 5a, ha&us teta6 5'

a-as'

Diltia5em dan Dantrolene

Salah satu,ya 5a6at me,',+9at9a, t*9s's'tas la',,ya 5e,+a, me9a,'sme: *bat te&sebut

'. 'ntoksikasi

Estu5' 9asus 9el*la &et&*s6e9t'< mela6*&9a, bah-a ,'


12/13

be&+*ya,+= mual= 9*,st'6as' 5a, e5ema 6e&'


13/13

Fa&ma9*l*+' 5a, Te&a6' FK UI

Fa&ma9*l*+' G**5ma, G'lma,

Fa&ma9*l*+' Dasa& Kl','9 Kat0u,+

I,

makalah farmako calcium antagonis

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