Berbagai macam rangsang Otot1Bonauli Simanjuntak

Reflex arc (lengkung Reflek)SISTEM SARAF PUSAT( OTAK/MS)RESEPTORSTIMULUSRESPONAFFERENEFFERENEFEKTOR(OTOT/KEL)

STIMULUS Reseptor; sbg transducerMekanik,Kimia,Faradis,Galvanis Osmotis,Suhu

Stimulus?

Sediaan Rheoskopis :Sediaan biologis yg dpt memberikan/memperlihatkan reaksi arus listrik dlm jar.hidup tanpa alat elektronik

Sediaan saraf-otot katak: N.Ischiadicus,M.Gastrocnemius dan Tendo Achilles

Perjalanan ImpulsRangsang Depolarisasi sp tercapai Threshold Potensial aksi dihantarkanSinaps Release Neurotransmitter post sinaps(reseptor post sinap)

Synaps?Neuron neuronNeuron otot (neuromuscular junction )

Neuromuscular Junction

Whole muscle( an organ)muscle fiber (a cell) myofibril (a specialized intracellular structure) thin and thick filamen (cytoskeletal filament) myosin and actin (protein)2nd ed.Sherwoood

Microscope:Antara grs Z ;Sarcomere( unit fungsional terkecil dari otot yang dpt berkontraksi)Z lines are places where actin filaments are anchored and define the limits of the sarcomere I bands are lighter bands where actin fibres do not overlap with myosin A bands are darker bands where myosin filaments are located M lines are the sites where myosin filaments are anchored

Thick: Myosin cross bridgeThin:Actin,tropomyosin,troponin Tropomyosin dan Troponin bekerjasama menutup/membuka Binding site actin

Excitation-Contraction Coupling-RelaxationAcH release from terminal motor end plate impuls is carried by T-TubulusT-Tubulus release Ca+ troponin catch open bindingbinding actin-myosinADP+P1 release

Rigor Mortis ?

Motor unit

1 motor unit : 1 motor neuron menginnervasi bbrp serat otot(muscle fibers).

Kontraksi isometric:otot tdk memendek/pjg otot konstanKontraksi isotonic:tension tetap

panjang otot!

Tetanic Contraction

Tetanic contraction:Kalau semua motor unit sudah tereksitasi.Perangsangan Subminimal Berturut-turut (perc.B)

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