Stabilitas Obat

Case

Stabilitas Obat

Members:

Rieneke Eoudia Han

Hairunisa

Desy Ratnasari

Utin Nur Kharunisa

Dini Sepkawila Caturizani

Windy Tri Agusta

Waktu (min)Log AmoksisilinN-benzoiamoksisilin40C50C60C70C40C50C60C70C30-2,125 x -2,138 x -2,504 x -2,689 x -1,902 x -3,935 x -4,799 x -6,006 x 60-3,297 x -4,368 x -5,636 x -1,403 x -4,495 x -7,667 x -1,295 x -1,336 x 90-4,272 x-7,598 x -1,399 x -3,188 x -7,841 x -1,211 x -2,058 x -2,337 x 120-5,125 x -1,013x -1,799 x -4,823 x -1,013 x -1,765 x -2,836 x -3,337 x 150-6,069 x -1,133 x -3,057 x -6,845 x -1,441 x-2,183 x -3.583 x -4,572 x Pers. RegY = -1,021. -1,439. Y= -1,525. + 1,093. Y= -2,591. + 2,764. Y= -3,314. + 1,481.

amoksisilin

Log

kt = - Log x 2,303Log

T= 40C

b = - 3,238

kt = -(-3,238) x 2,303

k (1) = 7,457 x

k = 7,457 x

T= 50C

b = - 8,048

kt = -(-8,048) x 2,303

k (1) = 1,854 x

k = 1,854 x

amoksisilin

T= 60C

b = - 2,282

kt = -(- 2,282.) x 2,303

k (1) = 5,257 x

k = 5,257 x

T= 70C

b = - 5,524

kt = -(- 5,524) x 2,303

k (1) = 1,272 x

k = 1,272 x

amoksisilin

T= 40C

k = 7,457 x

=

=

= 929,328

T= 50C

k = 1,854 x

=

=

= 373,786

T= 60C

k = 5,257 x

=

=

= 131,824

T= 50Ck = 1.272 x

= =

= 54,481

N-benzoilamoksisilin

Log

kt = - Log x 2,303Log

T= 40C

b = -1,021

kt = -(-1,021) x 2,303

k (1) = 2,352 x

k = 2,352 x

T= 50C

b = -1,525

kt = -(-1,525) x 2,303

k (1) = 3,512 x

k = 3,512 x

N-benzoilamoksisilin

T= 60C

b = - 2,591.

kt = -(- 2,591.) x 2,303

k (1) = 5,967 x

k = 5,967 x

T= 70C

b = - 3,314

kt = -(-3,314 ) x 2,303

k (1) =7,632 x

k = 7,632 x

N-benzoilamoksisilin

T= 40C

k = 2,352 x

=

=

= 294,517

T= 50C

k = 3,512 x

=

=

= 197,323

T= 60C

k = 5,967 x

=

=

= 116,529

T= 50Ck = 7,632 x

= =

= 90,801

Result

Maka, didapatkanlah nilai amoksisilin dan N-benzoilamksisilin pada suhu 40C, 50C, 60C dan 70C seperti yang tertera di jurnal pada tabel 6.

The End

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