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_aclgl hmdup, `anliyl`li jrlib parilh cu`l ltlu oadarl. @anliyl`li cu`l `aomc dlplt

sagnuh daibli saidmrmiyl tlipl parhltmli `husus, hlc mim dm`lrail`li jrlib ylib cu`l

gagmcm`m nlhli-nlhli dlslr ylib dmparcu`li uitu` paiyagnuhli cu`l sapartm supclm dlrlh

ou`up, smstag `a`anlcli utuh, stltus iutrmsm nlm`. Ilgui tmdl` sagul cu`l sagnuh daibli

saidmrmiyl, hlc mim dm`lrail`li ldliyl el`tjr-el`tjr mitarilc glupui a`starilc ylib

gaibblibbu ga`limsga paiyagnuhli. _ahmibbl dmparcu`li pailiblili `husus dlrm culr

uitu` gagnlitu paiyagnuhliyl.

Cltlr Nacl`lib Glslclh

_ajrlib cl`m-cl`m 41 tlhui, dltlib `a pjcm`cmim` `lrail dlarlh pmpm `mrm slgpmib oupmib

hmduib ldl cu`l ylib tmdl` sagnuh-sagnuh canmh dlrm dul nucli. Cu`l gl`mi clgl gl`mi

gacanlr dli gaidlclg. _udlh dmjnltm daibli jnlt cu`l tatlpm tmdl` ldl parnlm`li.

^ugusli Glslclh

_ajrlib cl`m-cl`m narusml 41 tlhui gaidarmtl cu`l `ucmt ylib tmdl` sagnuh-sagnuh, pldlhlc

sudlh dmnarm jnlt.

Lilcmsms Glslclh

Hmpjtasms

Cu`l @ucmtylib Tmdl`

_agnuh

_tru`tur @ucmt

Daemimsm Cu`l

dli Cu`l

@rjims

Emsmjcjbm

Vaiyagnuhli

Cu`l

Vaibhlgnlt

Vaiyagnuhli

Cu`l

@jgpcm`lsm

Cu`l @rjim`

Tarlpm Cu`l

@rjim`

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Cl`m-cl`m narugur 41 tlhui gaidarmtl `li`ar `ucmt

_lslrli Vagnaclklrli

. Glhlsmswl gaibatlhum daemimsm cu`l dli cu`l `rjim`

?. Glhlsmswl gaibatlhum emsmjcjbm paiyagnuhli cu`l

4. Glhlsmswl gaibatlhum el`tjr-el`tjr paibhlgnlt paiyagnuhli cu`l

1. Glhlsmswl gaibatlhum `jgpcm`lsm cu`l `rjim`

5. Glhlsmswl gaibatlhum tarlpm cu`l `rjim`

Vagnlhlsli

7/22/2019 Fisiologi Penyembuhan Luka dan Faktor Penghambat Luka Kronik

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4

Hmpjdargms ltlu sun`utli narldl pldl nlbmli tarnlwlh clpmsli `ucmt. Hmpjdargms

gaibliduib klrmibli ldmpjsl,emnrjncls, gl`rjelb, `acaiklr `armiblt, ejcm`ac rlgnut, slcurli

cmgeltm` dli pagnucuh dlrlh.1

>. Cu`l dli cu`l `rjim`

Cu`l ldlclh rusl` ltlu tarputusiyl `autuhli klrmibli ylib dmsanln`li saolrl emsm` ltlu

ga`lim`. _atmlp kaims cu`l gaimgnuc`li parldlibli, ylib garupl`li ral`sm tunuh tarhldlp

oadarl. Varldlibli dlplt dmdaemimsm`li sanlblm ral`sm klrmibli tarhldlp oadarl, ylib saolrl

`hls tardmrm ltls raspjis vls`uclr dli sacuclr, ylib saolrl narslgl-narslgl naruslhl

gaibhliour`li sunstlism ylib dm`ailcm sanlblm lsmib uitu` tunuh. Klrmibli mtu `agudmli

dmpucmh`li sapartm sadml`lcl ltlu dmparnlm`m sadagm`mli rupl lblr klrmibli ltlu jrbli mtu

dlplt nartlhli hmdup.5

Vaiyagnuhli saolrl mdalc naruslhl gagucmh`li klrmibli lslciyl, ilgui nmcl tmdl`

guib`mi, l`li tarnaitu` klrmibli plrut. ^ldlib ldl ylib l`ut dli ylib gailhui. Vaiyanln

plcmib ugug dlrm parldlibli ldlclh ) trlugl emsm`

(sarmib dmsartlm pardlrlhli dlclg klrmibli), ?) oadarl `mgmlwm, rldmlsm, ga`lim` ltlu targlc

(ylib clibsuib garlibslib klrmibli), 4) ral`sm mgui (gaimgnuc`li raspji hmparsaismtmvmtls

dlclg klrmibli).5

Tlnac

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1

Nardlslr`li clgliyl paiyagnuhli, cu`l dlplt dmbjcjib`li gaikldm dul yl`im02

Cu`l l`ut, garupl`li cu`l ylib nlru tarkldm ylib dlplt dmsagnuh`li sasulm

daibli clgl elsa paiyagnuhli ylib ijrglc (wl`tu paiyagnuhli dlplt

dmpar`mrl`li)

Cu`l `rjim`, garupl`li cu`l ylib taclh narclibsuib clgl `lrail paiyagnuhli

ylib ijrglc ltlu cu`l ylib sarmib `lgnuh (wl`tu paiyagnuhli cu`l tmdl` dlplt

dmpar`mrl`li).

Vldl paidarmtl cu`l l`ut, cu`l sahlrusiyl sagnuh saidmrm sataclh ? gmibbu dli tarkldm

ragjdaccmib. Vaidarmtl cu`l `rjim` tarhlgnlt dlclg prjsas paiyagnuhliyl, dlrm slclh sltu

elsa ylib ldl. Vaidarmtl cu`l `rjim` dlplt dmdaemimsm`li blblc saolrl urutli glupui

`atapltli wl`tu dlclg prjsas parnlm`li, ylib gaiomptl`li jrbli ylib samgnlib saolrl

liltjgm glupui euibsmjilc.

?. Emsmjcjbm paiyagnuhli cu`l

Tunuh naruplyl gagucmh`li `arusl`li klrmibli dli jrbli `agnlcm gaikldm stru`tur dli

euibsm ylib ijrglc daibli olrl gagnulib sac ylib sliblt rusl` sahmibbl tmdl` dlplt

nareuibsm `agnlcm dli gaibblitmiyl daibli sac nlru. Vrjsas emsmjcjbm paiyagnuhli cu`l

dlplt dmnlbm `a dlclg 4 elsa utlgl;8,=

M. ^aspjis mieclglsm l`ut tarhldlp oadarl; gaiol`up hagjstlsms, pacaplsli dlrm

gadmltjr (hmstlgmiuitu` gacanlr`li pagnucuh dlrlh ltlu vlsjdmcltlsm) dlrm sac-sac

ylib rusl` dli gmbrlsm sac dlrlh putmh (cau`jsmt pjcmgjrejiu`calr dli gl`rjelb) `a

tagplt ylib rusl` tarsanut.

MM. Elsa dastru`tme ldlclh elsa pagnarsmhli klrmibli ylib gltm dli ylib gaiblclgm

davmtlcmslsm jcah cau`jsmt pjcmgjrejiu`calr dli gl`rjelb.

MMM. Elsa prjcmearltme, ylmtu pldl sllt emnrjncls gacatl`li sunstlism dlslr dli sarlnut-

sarlnut `jclbai, sartl pagnaitu`li pagnucuh dlrlh `lpmcar nlru jcah tuils

aidjtacmlc (libmjbaiasms)0 tlidl-tlidl mieclglsm nar`urlib dli guouciyl klrmibli

brliucl ylib garupl`li paiyj`jib sunstlism dlslr dli sarlnut `jclbai.

MU. Elsa glturlsm gaiol`up ra-apmtacmslsm, `jitrl`sm cu`l jcah gyjemnrjncls dli

rajrblimslsm klrmibli m`lt jcahemnrjsmt.

Tlnac >. Elsa Vaiyagnuhli Cu`l

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Hjgajstlsms _abarl Vcltacats

Mieclglsm Hlrm < Gl`rjelb, Cmgejsmt, LibmjsmtIautrjsmt, Emnrjnclst,

@arltmijsmt

^agjdacmib Hlrm > tlhui Emnrjsmt

4. El`tjr-el`tjr paibhlgnlt paiyagnuhli cu`l

A`sudlt

A`sudlt garupl`li olmrli ylib `aculr dlrm cu`l ylib gaibliduib narnlblm

sunstlism sapartm lmr, aca`trjcmt, iutrmsm, sac gadmltjr mieclglsm, cau`jsmt, prjtalsa, dcc. Dlclgkugclh sadm`mt, a`sudlt nargliellt uitu` prjsas paiyagnuhli cu`l.A`sudltdmparcu`li

uitu` gaiklbl cmib`uibli ylib jptmglc nlbm paiyagnuhli cu`l dli nargliellt

gagnarm`li aea` gaiailib`li (sgjjthmib aeeaot) ukuib slrle ylib tarpliklib pldl

cu`l sahmibbl gagnlitu gaiburlibm iyarm cu`l. Tatlpm km`l kugclh a`sudlt pldl cu`l

narcanmhli, dlplt gaiyanln`li paimib`ltli rmsm`j miea`sm dli glsarlsm. @ucmt dm sa`mtlr

cu`l. _aclmi mtu, dm dlclg a`sudlt cu`l `rjim`, kugclh sac gadmltjr mieclglsm dli

prjtalsa gaimib`lt. Jcah `lrail mtu a`sudltylib narcanmhli hlrus dmhmclib`li dlrm cu`l,

gmslciyl daibli paibbuilli sultu drassmibpaiyarlp a`sudlt.2

Miea`sm

Miea`sm tmdl` hliyl gaibhlgnlt paiyagnuhli tatlpm kubl dlplt gagparnaslr

u`urli cu`l.2

Qsml

Gl`mi clikut usml, cu`l l`li gl`mi clgl sagnuh `lrail raspjis sac dlclg prjsas

paiyagnuhli cu`l l`li canmh clgnlt. Blibbuli supclm iutrmsm dli j`smbai pldl cu`l.

Blibbuli supclm iutrmsm dli j`smbai kubl dlplt gaibhlgnlt paiyagnuhli cu`l.2

_tltus Bmzm

Bmzm nuru` l`li gagparclgnlt paiyagnuhli cu`l `lrail `a`urlibli vmtlgmi,

gmiarlc, prjtami dli zlt-zlt clmi ylib dmparcu`li dlclg prjsas paiyagnuhli cu`l.2,8

Vaiyl`mt ylib Gaidlslrm

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Cu`l pldl paidarmtl dmlnatas gacmtus, liagml, uragml, lrtarmjs`carjsms, nmlsliyl

l`li sucmt sagnuh ltlu nlh`li dlplt gagnuru`.2,8

Garj`j`

_ultu studm gaiuiku``li nlhwl rj`j` dlplt gagparclgnlt paiyagnuhli lrail

dlplt garusl` emnrjncls ylib paitmib dlclg prjsas paiyagnuhli cu`l.2

_trass

_trass ylib narclibsuib clgl kubl l`li gaibhlgnlt paiyagnuhli cu`l.2,8

Jnlt-jnltli

Vaibbuilli starjmd ltlu mguijsuprasli klib`l pliklib dlplt gaiurui`li dlyl

tlhli tunuh ylib dlplt gaibhlgnlt paiyagnuhli cu`l.8

1. @jgpcm`lsm cu`l `rjim`

Vardlrlhli.

Hagltjgl.

Miea`sm,sapsms.

Blibrai.

_qulgus oaccs olromijgl.5,

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ylib gagpaiblruhm tarhaitmiyl prjsas paiyagnuhli cu`l. Tarhaitmiyl prjsas paiyagnuhli

cu`l dlplt gaiyanln`li `jgpcm`lsm sapartm0 pardlrlhli, hagltjgl, miea`sm, blibrai dli

gutlsm sac. Tarlpm elrgl`jcjbm glupui tarlpm iji-elrgl`jcjbm dlplt dm`jgnmilsm`li uitu`

gaibltlsm cu`l `rjim`.

Vldl glslclh dmltls plsmai gaiblclgm cu`l `rjim` dli dmourmblm gaidarmtl squlgus

oaccs olromijgl, uitu` mtu parcu dmcl`u`li nmjpsm uitu` gaibatlhum gutlsm pldl sac sahmibbl

dlplt dmcl`u`li pailiblili canmh clikut.

Dletlr pustl`l

6680 . GoBrlth K L, Aldy ^ L, Vjpa E G. ^jj`'s Taxtnjj` je Dargltjcjby(2th ad.).

Jxejrd; Nclo`wacc Vuncmshmib. p. ?.