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DAFTAR PUSTAKA 1. Honari G, Maibach HI. Chapter 1. Skin Structure and Function [Internet]. Applied Dermatotoxicology. Elsevier Inc.; 2014. 1-10 p. Available from: http://dx.doi.org/10.1016/B978-0-12-420130-9.00001-3 2. Sarkany RPE, Johns S. Ultraviolet Radiation and the Skin. 2011;(Roelandts 2007):46982. 3. Hurlow J, Bliss DZ. Dry Skin in Older Adults. Geriatr Nurs (Minneap) [Internet]. Mosby, Inc.; 2011;32(4):25762. Available from: http://dx.doi.org/10.1016/j.gerinurse.2011.03.003 4. Katagiri C, Sato J, Nomura J, Denda M. Changes in environmental humidity affect the water-holding property of the stratum corneum and its free amino acid content , and the expression of filaggrin in the epidermis of hairless mice. 2003;1:2935. 5. Barco D, Giménez-arnau A. Xerosis : a Dysfunction of the Epidermal Barrier. Actas Dermo-Sifiliográficas (English Ed [Internet]. Elsevier; 2008;99(9):67182. Available from: http://dx.doi.org/10.1016/S1578- 2190(08)70343-3 6. Baumann L. Understanding and Treating Various Skin Types : The Baumann Skin Type Indicator. 2008;26:35973. 7. Partogi D. Kulit Kering. Ilmu Kesehatan Kulit dan Kelamin FK USU; 2008. 8. Husna N, Purba D, Suryanto. Efek Pelembab Minyak Biji Bunga Matahari Dalam Sediaan Krim Tangan The Moisturizer Effect of Sunflower Seed Oil In Hand Cream Preparation. 2012;1(1):639. 9. Lodén M. Effect of moisturizers on epidermal barrier function. Clin Dermatol [Internet]. Elsevier Inc.; 2012;30(3):28696. Available from: http://dx.doi.org/10.1016/j.clindermatol.2011.08.015 10. Kapoor S, Project MP, Saraf S, Ph MP. Formulation and Evaluation of Moisturizer Containing Herbal Extracts for the Management of Dry Skin.

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DAFTAR PUSTAKA

1. Honari G, Maibach HI. Chapter 1. Skin Structure and Function [Internet].

Applied Dermatotoxicology. Elsevier Inc.; 2014. 1-10 p. Available from:

http://dx.doi.org/10.1016/B978-0-12-420130-9.00001-3

2. Sarkany RPE, Johns S. Ultraviolet Radiation and the Skin. 2011;(Roelandts

2007):469–82.

3. Hurlow J, Bliss DZ. Dry Skin in Older Adults. Geriatr Nurs (Minneap)

[Internet]. Mosby, Inc.; 2011;32(4):257–62. Available from:

http://dx.doi.org/10.1016/j.gerinurse.2011.03.003

4. Katagiri C, Sato J, Nomura J, Denda M. Changes in environmental

humidity affect the water-holding property of the stratum corneum and its

free amino acid content , and the expression of filaggrin in the epidermis of

hairless mice. 2003;1:29–35.

5. Barco D, Giménez-arnau A. Xerosis : a Dysfunction of the Epidermal

Barrier. Actas Dermo-Sifiliográficas (English Ed [Internet]. Elsevier;

2008;99(9):671–82. Available from: http://dx.doi.org/10.1016/S1578-

2190(08)70343-3

6. Baumann L. Understanding and Treating Various Skin Types : The

Baumann Skin Type Indicator. 2008;26:359–73.

7. Partogi D. Kulit Kering. Ilmu Kesehatan Kulit dan Kelamin FK USU;

2008.

8. Husna N, Purba D, Suryanto. Efek Pelembab Minyak Biji Bunga Matahari

Dalam Sediaan Krim Tangan The Moisturizer Effect of Sunflower Seed Oil

In Hand Cream Preparation. 2012;1(1):63–9.

9. Lodén M. Effect of moisturizers on epidermal barrier function. Clin

Dermatol [Internet]. Elsevier Inc.; 2012;30(3):286–96. Available from:

http://dx.doi.org/10.1016/j.clindermatol.2011.08.015

10. Kapoor S, Project MP, Saraf S, Ph MP. Formulation and Evaluation of

Moisturizer Containing Herbal Extracts for the Management of Dry Skin.

Pharmacogn J [Internet]. Pharmacognosy Network Worldwide

[Phcog.Net]; 2010;2(11):409–17. Available from:

http://dx.doi.org/10.1016/S0975-3575(10)80024-0

11. Ahmad Z. Complementary Therapies in Clinical Practice The uses and

properties of almond oil. Complement Ther Clin Pract [Internet]. Elsevier

Ltd; 2010;16(1):10–2. Available from:

http://dx.doi.org/10.1016/j.ctcp.2009.06.015

12. Hauser BM, Germany JCH. Cosmetic Oils in comparison : penetration and

occlusion of paraffin oil and vegetable oils. 2012;

13. Navarini AA, Valeyrie-allanore L, Setta-kaffetzi N, Barker JN, Capon F,

Creamer D, et al. Skin Is Not the Largest Organ Reply to Sontheimer. J

Invest Dermatol [Internet]. Nature Publishing Group; 2013;134(2):581–2.

Available from: http://dx.doi.org/10.1038/jid.2013.335

14. Integumentary System Part 1 [Internet]. 2011 [cited 2016 Jan 15].

Available from: http://antranik.org/integumentary-system-part-1/

15. Layers of the epidermis [Internet]. [cited 2016 Jan 15]. Available from:

http://higheredbcs.wiley.com/legacy/college/tortora/0470565101/hearthis_i

ll/pap13e_ch05_illustr_audio_mp3_am/simulations/hear/epidermis_layers.

html

16. Quinn AG. Biology of the skin and dermatological disease. 2004;1–3.

17. Badiu D, Luque R, Rajendram R. Effect of Olive Oil on the Skin [Internet].

Olives and Olive Oil in Health and Disease Prevention. Elsevier Inc.; 2010.

1125-1132 p. Available from: http://dx.doi.org/10.1016/B978-0-12-

374420-3.00123-6

18. Marks Jr. JG, Miller JJ. Structure and Function of the Skin. In: Lookingbill

and Marks’ Principles of Dermatology. 5th ed. China: Elsevier Inc.; 2013.

p. 4–16.

19. Paul C. Dermatitis. In: Acton QA, editor. Skin Diseases - Advances in

Research and Treatment. Atlanta: ScholaryEditions; 2012. p. 58.

20. Dewi DAR. Penambahan Saccharide Isomerates 5% dalam Formulasi

Pelembab Meningkatkan Hidrasi Kulit Lebih Tinggi Dibandingkan

Pelembab Biasa. 2010.

21. Tranggono RI, Latifah F. Kosmetik Pelembab dan Pelindung. In:

Djajadisastra J, editor. Buku Pegangan Ilmu Pengetahuan Kosmetik.

Jakarta: Gramedia Pustaka; 2007. p. 75–89.

22. Jahanban A, Jamei R, Jahanban R. The importance of almond ( Prunus

amygdalus L .) and its by-products. Food Chem [Internet]. Elsevier Ltd;

2010;120(2):349–60. Available from:

http://dx.doi.org/10.1016/j.foodchem.2009.09.063

23. Kang BC, Kim YE, Kim YJ, Chang MJ, Choi HD, Li K, et al. Optimizing

EEMCO guidance for the assessment of dry skin (xerosis) for pharmacies.

2014;(2):87–91.

24. Tjekyan S. Perbandingan Efektivitas Krim Urea 10% dan Krim Niasiamid

4% pada Xerosis Usia Lanjut. J Kedokt dan Kesehat. 2015;2(1):54–60.

25. Ravindra T, R PP, H PP. JOURNAL OF PHARMACEUTICAL AND

BIOMEDICAL SCIENCES Formulation and Evaluation of Semisolid

preparation ( Ointment , Gel & Cream ) of Thiocolchicoside Abstract :

Introduction : 2011;8(01).

26. Levin J, Miller R. REVIEW ] A Guide to the Ingredients and Potential

Benefits of Over-The-Counter Cleansers and Moisturizers for Rosacea

Patients. 2011;4(8):31–49.

27. Kapoor S, Saraf S. Assessment of Viscoelasticity and Hydration Effect of

Herbal Moisturizers Using Bioengineering Techniques. Pharmacogn Mag

[Internet]. 2010;6(24):298–304. Available from:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992143/

28. Amon U, Erndt S. Evaluation of a Moisturizing Cream Containing Sweet

Almond Oil and Gyceryl Polymethacrylate in Patients with Chronic

Inflammatory Skin Diseases. J allergy clin immunol Vol 119, number 1.

2007;119(1):816.

29. Sweet Almond oil [Internet]. 2006 [cited 2016 June 14]; 3:1–4. Available

from:

http://www.centerchem.com/Products/DownloadFile.aspx?FileID=6849

Lampiran 1. Ethical clearance

Lampiran 2. Contoh informed consent

Lampiran 3. Kuesioner penelitian

FORM PENELITIAN

Nama : ………………………………………………………………

Usia : ………………………………………………………………

Alamat : ………………………………………………………………

………………………………………………………………

No telp :……………………………………………………………….

ANAMNESIS

Berikan tanda centang (√) pada jawaban pilihan anda!

1. Tipe kulit:

Normal Kering

2. Apakah anda mempunyai riwayat alergi kulit?

Ya Tidak

3. Jika Ya, sebutkan:

4. Apakah anda mempunyai riwayat penyakit kulit?

Ya Tidak

5. Jika Ya, sebutkan:

6. Apakah anda mengonsumsi obat-obatan tertentu secara rutin?

Ya Tidak

7. Jika Ya, sebutkan:

8. Berapa kali Anda mandi dalam sehari?

<2 kali 2-3 kali >3 kali

9. Berapa jam dalam sehari kira-kira Anda terpapar sinar matahari?

0-3 jam 6-9 jam > 12 jam

3-6 jam 9-12 jam

10. Berapa jam dalam sehari Anda berada dalam ruangan berpendingin atau AC?

0-3 jam 6-9 jam > 12 jam

3-6 jam 9-12 jam

Lampiran 4. Hasil analisis data

Ranks

N Mean Rank Sum of Ranks

H28 - H0

Negative Ranks 20a 11.03 220.50

Positive Ranks 1b 10.50 10.50

Ties 37c

Total 58

a. H28 < H0

b. H28 > H0

c. H28 = H0

Test Statisticsa

H28 - H0

Z -4.082b

Asymp. Sig. (2-tailed) .000

a. Wilcoxon Signed Ranks Test

b. Based on positive ranks.

Ranks

N Mean Rank Sum of Ranks

H28 - H0

Negative Ranks 4a 3.00 12.00

Positive Ranks 1b 3.00 3.00

Ties 24c

Total 29

a. H28 < H0

b. H28 > H0

c. H28 = H0

Tests of Normality

Group Kolmogorov-Smirnova Shapiro-Wilk

Statistic df Sig. Statistic df Sig.

H0

kelompok kontrol .261 29 .000 .791 29 .000

kelompok perlakuan (almond oil

4%)

.261 29 .000 .791 29 .000

H28

kelompok kontrol .299 29 .000 .756 29 .000

kelompok perlakuan (almond oil

4%)

.501 29 .000 .460 29 .000

a. Lilliefors Significance Correction

Ranks

Group N Mean Rank Sum of Ranks

delta

kelompok kontrol 29 23.21 673.00

kelompok perlakuan

(almond oil 4%)

29 35.79 1038.00

Total 58

Test Statisticsa

Delta

Mann-Whitney U 238.000

Wilcoxon W 673.000

Z -3.379

Asymp. Sig. (2-tailed) .001

a. Grouping Variable: group

Test Statisticsa

H0

Mann-Whitney U 34.500

Wilcoxon W 187.500

Z -3.234

Asymp. Sig. (2-tailed) .001

Exact Sig. [2*(1-tailed Sig.)] .002b

a. Grouping Variable: tipe_kulit

b. Not corrected for ties.

Ranks

tipe_kulit N Mean Rank Sum of Ranks

H0

kering 12 20.63 247.50

normal 17 11.03 187.50

Total 29

Tests of Normality

alergi Kolmogorov-Smirnova Shapiro-Wilk

Statistic df Sig. Statistic df Sig.

H0 ya .473 5 .001 .552 5 .000

tidak .234 24 .002 .809 24 .000

a. Lilliefors Significance Correction

Ranks

sakit_kulit N Mean Rank Sum of Ranks

H0

ada riwayat penyakit kulit 8 12.06 96.50

tidak ada riwayat penyakit

kulit

21 16.12 338.50

Total 29

Test Statisticsa

H0

Mann-Whitney U 60.500

Wilcoxon W 96.500

Z -1.241

Asymp. Sig. (2-tailed) .215

Exact Sig. [2*(1-tailed Sig.)] .257b

a. Grouping Variable: sakit_kulit

b. Not corrected for ties.

Ranks

obat N Mean Rank Sum of Ranks

H0

mengonsumsi obat-obatan

rutin

1 27.00 27.00

idak mengonsumsi obat-

obatan rutin

28 14.57 408.00

Total 29

Test Statisticsa

H0

Mann-Whitney U 2.000

Wilcoxon W 408.000

Z -1.552

Asymp. Sig. (2-tailed) .121

Exact Sig. [2*(1-tailed Sig.)] .207b

a. Grouping Variable: obat

b. Not corrected for ties.

Ranks

mandi N Mean Rank

H0

<2 kali/hari 3 14.50

2-3 kali/hari 26 15.06

Total 29

Test Statisticsa,b

H0

Chi-Square .014

df 1

Asymp. Sig. .907

a. Kruskal Wallis Test

b. Grouping Variable:

mandi

Ranks

sinar_matahari N Mean Rank

H0

<3 jam/hari 17 15.06

3-6 jam/hari 10 14.55

6-9 jam/hari 2 16.75

Total 29

Test Statisticsa,b

H0

Chi-Square .133

df 2

Asymp. Sig. .936

a. Kruskal Wallis Test

b. Grouping Variable:

sinar_matahari

Ranks

AC N Mean Rank

H0

<3 jam/hari 1 18.50

3-6 jam/hari 7 11.64

6-9 jam/hari 8 18.69

9-12 jam/hari 4 6.50

>12 jam/hari 9 17.72

Total 29

Test Statisticsa,b

H0

Chi-Square 8.972

df 4

Asymp. Sig. .062

a. Kruskal Wallis Test

b. Grouping Variable: AC

Lampiran 5. Dokumentasi penelitian

Lampiran 6. Biodata peneliti

Identitas

Nama : Christian Tricaesario

NIM : 22010112130134

Tempat/tanggal lahir : Jakarta, 24 November 1993

Jenis kelamin : Laki-laki

Alamat : Jurang Mangu Permai G3/1A, Tangerang Selatan, Banten

Nomor HP : 081808604662

e-mail : [email protected]

Riwayat Pendidikan Formal

1. SD : Ricci II Lulus tahun: 2005

2. SMP : Ricci II Lulus tahun: 2008

3. SMA : Santa Ursula BSD Lulus tahun: 2011

4. FK Undip : Masuk tahun: 2012

Keanggotaan Organisasi

1. Divisi Promosi dan Publikasi AMSA-Undip Tahun 2013

2. Ketua/Representative AMSA-Undip Tahun 2014

3. Advisory Board AMSA-Undip Tahun 2015

4. Departemen Keilmuan PMKK FK Undip Tahun 2015

5. PSM Undip Tahun 2013 s/d 2015

Pengalaman presentasi karya ilmiah

1. Christian Tricaesario, Indi Swastyastika. Judul: Konjugasi fVII dengan R10b

Allium sativum sebagai Upaya Kuratif Endometriosis. Forum: SPORA. Tahun

2015

Cara presentasi oral

2. Christopher Octavianus, Christian Tricaesario.Judul: CS-P/shSREBP sebagai

Kombinasi Terapi Mutakhir Diabetes Mellitus Tipe 2. Forum: IMSS. Tahun 2016

Cara presentasi poster

Pengalaman mengikuti lomba karya ilmiah

1. Christopher Octavianus, Christian Tricaesario, Indi Swastyastika. Konjugasi

fVII dengan R10b Allium sativum sebagai Upaya Kuratif Endometriosis. FK

Unsri. Finalis ke-5

2. Christopher Octavianus, Christian Tricaesario. CS-P/shSREBP sebagai

Kombinasi Terapi Mutakhir Diabetes Mellitus Tipe 2. BAPIN ISMKI dan FK

Unissula. Finalis