8/2/2019 _497715266c316aeecb42cc1af889f035_Unair

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Dokumen Artikel Penelitian ini milik penulis/penelliti yang diserahkan sebagian (judul dan Abstrak) hak ciptanya kepada Universitas Airlangga untukdigunakan referensi dalam penulisan artikel ilmiah.

Penulis : MIA RATWITA ANDARSINIFakultas : Kedokteran

Tim Peneliti : I Dewa Gede Ugrasena, dr., SpA(K)., FADIL RULIAN, MARIA CHRISTINA SHANTY LARASATI, BAMBANG PERMONO ,

HIV INFECTION IN HB E THALASSEMIA CHILD

Abstrak :

Background:Children with thalassemia major survive mainly on regular blood transfusions, which may

expose them to different transfusion-transmitted infections (TTIs), especially hepatitis B, hepatitis C, HIV,

and Treponema pallidum. The risk of HIV transmission is estimated to be 1:1.930.000, although it isdifficult to be precise with such a low incidence.

Objective:To report a case of HIV infection in a child with Hb E Thalassemia

Case Report:R, 14 year-old girl with Hb E Thalassemia, has received regular blood transfusion in

Tulungagung and Surabaya

hospital since she was 3 years old. She was planned to undergo splenectomy because of the massive

enlargement of spleen which causes concern about possible splenic rupture. Preoperation laboratory

examination for HIV infection using ELISA method was positive but CD4 absolut was normal and Hbs Ag

or anti HCV were negative. The ELISA method for HIV infection examination for her parents was negative.

There were no history of drug abuse, sexual intercourse, reuse of contaminated needles and syringe, and

tattoing/traditional piercing. The antiviral drug has not been given because CD4 absolute level was more

than 500 cell/uL and the patient was in a good condition.Conclusion:A

case of HIV infection in a child with HbE Thalassemia, we assumed HIV infection was acquired through

regular transfusion.

Keywords :

thalassemia, blood transfusion, HIV infection

Keyword :

thalassemia, blood transfusion, HIV infection

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