makalah bph dll

7/26/2019 Makalah BPH dll

1/15

BAGIAN ILMU BEDAH

FAKULTAS KEDOKTERAN MAKALAH

UNIVERSITAS HASANUDDIN APRIL 2016

BENIGN PROSTAT HIPERPLASIA: ETIOLOGI DAN BIOMARKER

OLEH:

RINOLDY PUTRA MANGIRIC111 10 173

SUPERVISOR :

dr SYAKRI SYAHRIR! S"U

DIBA#AKAN DALAM RANGKA TUGAS KEPANITERAAN KLINIKPADA BAGIAN ILMU BEDAH

FAKULTAS KEDOKTERAN

UNIVERSITAS HASANUDDIN

MAKASSAR

2016


2/15

BAB I

PENDAHULUAN

1.1 Latar Belakang

BPH adalah keadaan yang dikenal dengan pembesaran prostat yang

disertai dengan gangguan pada traktus urinarius bagian bawah.Beberapa mekanisme sering diimplikasikan terhadap patolfsiologidari BPH. Baik itu perubahan jaringan akibat usia, alterasi hormone,dan sindrom metabolic dan inamasi. Meskipun androgens bukanlahpenyebab dari BPH.

Benign prostat hyperplasia (BPH hampir kebanyakan dialami olehpria pada umur lebih dari !" tahun dan muncul sebagai kasusurologi tertinggi pada laki#laki yang telah berumur. $anda klinis BPHdidefnisikan dengan kombinasi antara gangguan pada traktusurinarius bagian bawah dengan pembesaran prostat yang benignadan obstruksi pengeluaran urin. %ejala BPH bisa muncul darigangguan retensi urin minimal sampai ke kegagalan ginjal.Beberapa pasien muncul tanpa gejala, meskipun BP% didiagnosadengan pemeriksaan histologi. &iagnosa histologi BPH mengacupada pembesaran berlebihan dari komponen epitel dan stroma dari'ona transisi dan area periurethra. Prealensi dari BPH daptmenjadi )*"+ pada umur " tahun dan )-"+ pada umur *" tahun.Meskipun androgen dan estrogen telah dilibatkan dalam penelitianakan BPH, mekanisme dari sel dan molekul yang menekankantentang pathogenesis BPH dan mengarahkan pada gejala pada

penyakit masih sepenuhnya belum diketahui.

1.2 Rumuan Maala!

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3/15

BAB II

ISI

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4/15

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6/15

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14/15

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DAFTAR PUSTAKA

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15/15

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201?

> G-+r+$$K$r+%& M! M+,()4+ A Pr(&)&)%' M(/$,/+r T+r'$*) +%d

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