kimia farmasi medisinal ii- ranitidine antihistamin.pptx
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KIMIA FARMASI MEDISINAL II
RANITIDINE
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NAMA KELOMPOK 5:
1. TRISTIYANTO ANGGA PRATAMA NPM : 1343050028
2. MAYA NURHIJRIAH NPM : 1343050031
3. INGGAR DEO NPM : 1343050034
4. FAKHRI DIENUL HAQ NPM : 1343050038
5. INDRI APRIYANTI PUTRI NPM : 134305009
. NA!ILA FAU"IAH NPM : 1343050130
#. AL$IN O%TA$IANUS NPM : 134305014#
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RANITIDINE ANTIHISTAMIN
Antihistamin adalah zat-zat yangdapat mengurangi atau menghalangi
efek histamin terhadap tuuh dengan!alan meml"k resept"r # histamine$penghamatan saingan%&
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HISTAMIN
H&I
H&2H&3
H&4
O'(' )(*(+ E,-('*/ O'
M(+ ++ O'(' ,', ('
O' P*++
/,'6/ S* +76
E+/,(/* N'6(/* S* T&%D4
S-, -/,,
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ANTIHISTAMIN
ANTAGONIS
RESEPTOR
H&1
ANTAGONIS
RESEPTOR
H&2
-/+' H1&*(6+
' ,'/;/+'/,/
H2&*(6+ '
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P6(++ '6-/,7 = ' *,
)(* ;/-)
/' '/-
'6'6 -,
+;'.
> + ?H @6*/;
M6+*)/+, (+
-,+(+
L '
)6-,,
)- +*)'
*,-/6
M= '*,
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M,/+ +/
H&2RANITIDINE
H2-blockers/
antagonis
reseptor H-2
1. M,;' +/ ;/+'/, -/ 6+)'(6 H2 +6 ()'/'/ -, +*'/ -/ +*
)6/'*,;' +6+/ + *, ? (* *, 66,B -,
(,+,'6+/ /(, ;/-6(, 66,@
2. H2 ,'(,/+ -*; /,;//'(6 ()'/'/ ;/+'/, )- 6+)'(6 H2 +* )6/'*.
M6 ,, +6+/ + ,(6* ?*/@ (*; +* )6/'* -, +6+/ +
7, -/6,+, ,. M6 *,,7 -,, - ,/+:
.;/+'/, 7, -/*)+, (*; +*&+* E%L -* )6' -/*(/6 -6/ ),/',
-,, 6+)'(6 H2 +* )6/'* 7, 6,+, +6+/ +B.M,;'
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K/6/), S'6'6
RANITIDINE
?,'(,/+
;/+'/, H&2@
HISTAMIN
?A(,/+@
/,/,
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S6; 6,/'/-/,
H/+'/,
A(,/+ */4-metilhistamin
(,/+ ',
%/,/,
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S6; 6,/'/-/,
P,,'/, + ,/-/,
?6+/' )(+/'/@ -,, + '/(6?'/- 6', -, )(*6@
(,/+ ;/*, -, H2&,'(,/+
'
%(,'(; : !6/,,/-
,,'/ + '/(6 -,, + N&
+/,(,/-/,),;' 6+)'(6
H2)6'
%(,'(; : +/'/-/,
M6), +,7C ,*(
+/'/-/, -,, ),,'/, /,/,
//-
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F6(/,'/ 6-+6, +'6'6
M(-//+/ /+('6/ -6/ /,'//-
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F6(/,'/ 6,/'/-/,
R,/'/-/, ,*/ '(*/+ */,'+ )6' -/ ;'/ -* *; 7, )
+6 +'*; )6/, (6*. R,/'/-/, -, '(*/',7 -/+6+/ '6' **/
/,*B +/+,7 **/ '/,. S/'6 #0 -6/ 6,/'/-/, 7, -/6/, I$ -, 30 7,
-/6/, +6 (6* -/+6+/ -* 6/, -* ,' +*.
!/(/*/*/'+ 6,/'/-/, 7, -/6/, +6 (6* +/'6 50 -, ,/,'
)- )+/, ),7/' ;'/. M+ )6;,7 /6&/6 1B# &3 )- (6, -C+B -,
,, )- (6, ' -, )+/, * /,*.
K-6 ), )*+ -/)/ -* 1&3 +'*; ),,, 6,/'/-/, 150
+6 (6*B -, '6/' )6('/, )*+ ;,7 15 .
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DAFTAR PUSTAKA
Y(*,-B A6/,'. 2011. F6(*(/ O' A,'/;/+'/,
S/+C,-(,( +(6-(B !,.2008.kimia medisinal 1.A/6*, U,/6+/'7
P6++.S67
;''):==-/+'(6.(=6'/*=25=M-,A,'+/-.;'*
S()6,. 2001.IlmyPenyakit Dalam. Jilid 11. Ed. 3. J6' : FKUI.
http://medicastore.com/artikel/265/Maag_dan_Antasida.htmlhttp://medicastore.com/artikel/265/Maag_dan_Antasida.html -
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