gangguan imun 2010 1

7/23/2019 GANGGUAN IMUN 2010 1

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A.GIT

diare, muntah

B. Trac. Resp

asma, rinitis

C. KULIT

ekzem, urtikaria


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I. Immediate Hypersensitivities.

These ccur !uick"y a#ter

e$psure t the a""er%en.They are usua""y mediated &y

anti&dies # the I%. ' c"ass.


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7/44

(enyakit )

Kn*un%tivitis

Asma Rinitis

Ana#i"aktic shck

'#ek mediatr kimia )

+ vasdi"atasi, hipersekresi,edem, &rnk spasme


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II. Anti&dy-ediated Cytt$icity

I% G, I% -/

Ce"" dama%e caused &y

anti&dies directed a%ainst ce""

sur#ace anti%ens

pd. 0e" K, -akr#a%/


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A%

A%


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Anemia hem"itik


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III.Immune Cmp"e$1isrders

1ama%e caused &y the depsitin the tissues # cmp"e$es #

anti%en and their anti&dies


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(enyakit )

the prtzans that cause ma"aria

the 2rms that causeschistsmiasis and #i"ariasis

the virus that causes hepatitis B,demam &erdarah.

0ystemic "upus erythematsus 0L'/

34armer5s Lun%6 &atuk, sesak na#as/


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0erin% dise&a&kan serum imunisasi/

thd. 1ipteri atau tetanus

G$. 1ise&ut d%. 0yndrma sickness

#ever

Hives7urticaria

arthritis prtein in the urine.


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I8.Ce""-ediated Hypersensitivities

tipe "am&at/


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T9. AL'RGI

Antihistamines

Mast Cell Stabilizers

Corticosteroids


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AL'RGI 1A: AUTI0-' ?????


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ke%a%a"an #un%si sistem

keke&a"an tu&uh yan%mem&uat &adan

menyeran% *arin%annyasendiri.


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T';RI AUT;I-U:


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=. de#esiensi immune

>.1eterminan anti%en &aru

(em&entukan autoantibodydicetuskankarena tim&u" determinan anti%en &arupada prtein nrma". -is. rematoid

?.Reaksi si"an% den%an mikrr%[email protected]

. Autanti&di di&entuk sekunder aki&at

kerusakan *arin%an.


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Kriteria mene%akkan

dia%nsis penyakitautimun )

autanti&dy

(':AKIT AUT;I-U: )


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(':AKIT AUT;I-U: )

1. Anemia hemolitik

(autoantibodi antierytrosit)

2. SINDROM SJOGREN.

- ditandai : keratokonjungtivitis sikka(mata kering ) !erostomia (mu"ut

kering)

- #N#$anti nu%"ear anti&od').


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>. -yasthenia %ravis

neurmuscu"ar/

Autanti&di acety"ch"ine


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?. (ernicius anemia AUT;A:TIB;1I B


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T9 )Immunsupresant )

azathiprine, ch"ram&uci",cyc"phsphamide, cyc"sprine,mycphen"ate, dan methtre$ate

krtiksterid, seperti prednisnUntk. -en%uran%i G9. )

'tanercept, in#"i$ima&, danada"imuma& men%ha"an%i aksi T:4

("asmapheresis


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G':'TIK

;&at atau tksin

(':AKIT -'TAB;LIK ATAU:UTRI0I

Ke"ainan krmsm

I:4'K0I


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0'L T, 0'L B

:;: 0('0I4IK

G':'TIK7BAAA:

B:AK (1. A:AK

'tiI"%i ) Krn.

(enyakit "ain, umur,

&at, nutrisi


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. I% A 1e#isiensi D 0'L B, 0'L T

?. 1i%er%e 0yndrme Thymic

Hypp"asia/@. Genetic 1e#iciencies # the

Cmp"ement


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I-U:1'4. 0'KU:1'R7

ACEUIR'1


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(':'BAB )

Human

immunde#iciency virus

1i darah, cairan

sperma, cairan va%ina

dan air susu i&u


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0'L TARG'T ) se" dendritik dan C1


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KLI:I0 )

+I:KUBA0I >


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A. Resrpsi t". A"ve"aris B. artz

C. 1. Kapsiss sarkma


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T9 ) K;-BI:A0I I1;8U1I:,1I1A:;0I:', 0TA8U1I:',

ALCITABI:', LA-I8U1I:'

1A: (R;T'A0' I:HIBIT;Rindinavir, ne"#ina#ir, ritnavir,

sa!uinavir/

(':G;BATA:


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(':G;BATA: suprti#, ke&utuhan %izi dan ka"ri, men*a%a

keseim&an%an cairan, e"ektr"it, dan asam&asa,

ke&utuhan ksi%en, serta me"akukan usahapence%ahan in#eksi

su&stitusimem&erikan eritrsit, "euksit, p"asma&eku, enzim, serum hiper%ama%"&u"in,

%ama%"&u"in, imun%"&u"in spesi#ik. imunmdu"asi,inter#ern/, anti&dimnk"na", prduk mikr&a BCG/, prduk&i"%ik timsin/, kmpnen darah atau prdukdarah

kausa".terutama pada de#isiensi imun sekunderpen%&atan in#eksi, sup"emen %izi, pen%&atanke%anasan, dan "ain"ain/.

1e#isiensi imun primer transp"antasi timus,

hati, sumsum tu"an%/ atau rekayasa %enetik.


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gangguan imun 2010 1

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