vii

DAFTAR ISI

HALAMAN JUDUL ................................................................................................ i

HALAMAN PENGESAHAN ................................................................................. ii

SURAT PERNYATAAN....................................................................................... iii

PRAKATA ............................................................................................................. iv

DAFTAR ISI ......................................................................................................... vii

DAFTAR GAMBAR ............................................................................................. xi

DAFTAR SINGKATAN ...................................................................................... xii

DAFTAR TABEL ................................................................................................ xiii

DAFTAR LAMPIRAN ........................................................................................ xiv

INTISARI ............................................................................................................. xvi

BAB I PENDAHULUAN ........................................................................................ 1

1.1 Latar Belakang .................................................................................... 1

1.2 Rumusan Masalah ............................................................................... 2

1.3 Tujuan Penelitian ................................................................................ 3

1.3.1. Tujuan Umum ......................................................................... 3

1.3.2. Tujuan Khusus ........................................................................ 3

1.4 Manfaat Penelitian .............................................................................. 3

1.4.1. Manfaat Teoritis ...................................................................... 3

1.4.2. Manfaat Praktis ....................................................................... 4

BAB II TINJAUAN PUSTAKA .............................................................................. 5

2.1 Camera Oculi Anterior (COA) ........................................................... 5

2.2 Humor Akuos ...................................................................................... 6

viii

2.2.1 Definisi dan Fungsi ................................................................. 6

2.2.2 Anatomi dan Fisiologi ............................................................. 7

2.3 Tekanan Intraokular ( TIO ) ................................................................ 8

2.4 Glaukoma ............................................................................................ 9

2.4.1 Definisi .................................................................................... 9

2.4.2 Etiologi dan Faktor Risiko ...................................................... 9

2.4.3 Klasifikasi ............................................................................... 9

2.4.4 Patogenesis dan Patofisiologi................................................ 10

2.5 Terapi Bedah dan Laser .................................................................... 14

2.5.1 Trabekulektomi ..................................................................... 14

2.5.2 Iridoplasti, Iridektomi dan Iridotomi Perifer......................... 15

2.5.3 Ekstraksi Katarak .................................................................. 15

2.6 Katarak .............................................................................................. 16

2.6.1 Katarak Senilis ...................................................................... 16

2.7 Bedah Katarak ................................................................................... 17

2.7.1 Ekstraksi Katarak Intra Kapsular (EKIK) ............................. 17

2.7.2 Ekstraksi Katarak Ekstra Kapsular (EKEK) ......................... 17

2.7.3 Fakoemulsifikasi ................................................................... 17

2.8 Komplikasi operasi katarak .............................................................. 18

2.9 Hubungan Ekstraksi Katarak dengan Peningkatan Kedalaman

COA .................................................................................................. 19

2.10 Kerangka Teori ................................................................................. 20

2.11 Kerangka Konsep .............................................................................. 20

ix

2.12 Hipotesis ........................................................................................... 21

BAB III METODE PENELITIAN......................................................................... 22

3.1 Jenis Penelitian dan Rancangan Penelitian ....................................... 22

3.2 Variabel Penelitian dan Definisi Operasional ................................... 22

3.2.1 Variabel ................................................................................. 22

3.2.2 Definisi Operasional ............................................................. 22

3.3 Populasi dan Sampel ......................................................................... 23

3.3.1 Populasi ................................................................................. 23

3.3.2 Sampel ................................................................................... 23

3.4 Instrumen penelitian ......................................................................... 25

3.5 Cara Penelitian .................................................................................. 25

3.5.1 Studi Pendahuluan................................................................. 25

3.5.2 Pelaksanaan Penelitian .......................................................... 26

3.6 Alur Penelitian .................................................................................. 27

3.7 Pengolahan Data ............................................................................... 27

3.8 Tempat dan Waktu Penelitian ........................................................... 28

3.8.1 Tempat .................................................................................. 28

3.8.2 Waktu .................................................................................... 28

3.9 Analisis Hasil .................................................................................... 28

BAB IV HASIL PENELITIAN DAN PEMBAHASAN ....................................... 29

4.1 Hasil Penelitian ................................................................................. 29

4.2 Pembahasan ...................................................................................... 31

BAB V SIMPULAN DAN SARAN ...................................................................... 35

x

5.1 Kesimpulan ....................................................................................... 35

5.2 Saran ................................................................................................. 35

DAFTAR PUSTAKA ............................................................................................ 36

LAMPIRAN ........................................................................................................... 40

xi

DAFTAR GAMBAR

Gambar 2. 1. Camera Oculi Anterior (Gray’s Anatomi, 2008) ............................. 5

Gambar 2. 2. Kerangka Teori ................................................................................. 20

Gambar 2. 3. Kerangka Konsep ........................................................................... 20

Gambar 3. 1. Alur Penelitian ................................................................................ 27

Gambar 4. 1. Rata-rata kedalaman COA pada pasien glaukoma sudut tertutup

akut pra dan pasca fakoemulsifikasi ............................................... 31

xii

DAFTAR SINGKATAN

COA : Camera Oculi Anterior

TIO : Tekanan Intrakokuler

COP : Camera Oculi Posterior

GLC1A : Chromosome 1 Open-Angle Glaucome

RSI : Rumah Sakit Islam

SEC : Sultan Agung Eye Center

1q23-q25 : Kromosom 1 lengan q lokus ke-23 sampai lokus ke-25

xiii

DAFTAR TABEL

Tabel 4. 1 Deskripsi karakteristik pasien glaukoma sudut tertutup akut

berdasar jenis kelamin dam usia.......................................................... 29

Tabel 4.2. Hasil analisis kedalaman COA antara pra dan pasca

fakoemulsifikasi pada pasien glaukoma sudut tertutup akut ............... 30

xiv

DAFTAR LAMPIRAN

Lampiran 1. Hasil Penelitian .................................................................................. 40

Lampiran 2. Distribusi karakteristik pasien glaukoma sudut tertutup akut yang

menjalani fakoemulsifikasi di SEC Semarang ............................... 41

Lampiran 3. Hasil Uji Deskriptif Statistik, Normalitas Sebaran Data dan

Homogenitas Varian Kedalaman COA pra dan pasca

Fakoemulsifikasi ............................................................................. 42

Lampiran 4. Hasil Uji Paired Sample T-Test Perbedaan Kedalaman COA pra

dan pasca Fakoemulsifikasi ............................................................ 44

Lampiran 5. Hasil analisis deskriptif, normalitas dan homogenitas varian data

kedalaman COA pra dan pasca fakoemulsifikasi menurut jenis

kelamin pasien ................................................................................ 45

Lampiran 6. Hasil analisis deskriptif, normalitas dan homogenitas varian data

kedalaman COA pra dan pasca fakoemulsifikasi menurut posisi

mata 47

Lampiran 7. Hasil analisis deskriptif usia pasien glaukoma sudut tertutup

akut yang menjalani fakoemulsifikasi ............................................ 49

Lampiran 8. Hasil analisis deskriptif perbedaan kedalaman COA pra dan

pasca fakoemulsifikasi menurut jenis kelamin ............................... 50

Lampiran 9. Ethical clearance ............................................................................... 51

Lampiran 10. Surat keterangan mulai penelitian di Rekam Medis RS Islam

Sultan Agung .................................................................................. 52