efek antipiretik phylantus
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LEMBAR PERSETUJUAN
JUDUL : EFEK ANTIPIRETIK INFUSA MENIRAN
(Phyllanthus niruriLinn.) TERHADAP MENCIT
JANTAN GALUR SWISS WEBSTER
PENYUSUN : FENTY D. BARUS
NRP : 07101!
BANDUNG" JANUARI 011
MENYETUJUI"
PEMBIMBING UTAMA PEMBIMBING PENDAMPING
R#$n%&ni" '%."A* D+,$&nn%"'."AIF
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SURAT PERNYATAAN
Y%n- &*%n'% *%n-%n 'i%/% ini :
N%% : F&n*2 D. B%,$
NRP : 07101!
M&n2%*%3%n %/% K%2% T,4i$ I4i% ini %'%4% %$i4 3%2% $&n'ii" ,3%n
',4i3%$i '%i 3%2% #%n- 4%in.
A%i4% 'i3&,'i%n %i 'i3&*%,i ini *i'%3 &n%" %3% $%2% &$&'i%
&n&i% $%n3$i $&$,%i %*,%n 2%n- &4%3,.
D&i3i%n &n2%*%%n $%2%
B%n',n-" F&,%i 01
F&n*2 D.B%,$
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ABSTRAK
EFEK ANTIPIRETIK INFUSA MENIRAN (Phyllanthus niruriLinn.)TERHADAP MENCIT JANTAN GALUR SWISS WEBSTER
F&n*2 D. B%,$" 0115 P&iin- I : R#$n%&ni" '%."A*
P&iin- II : D+,$&n%" '."AIF
D&% %'%4% -&+%4% 2%n- %4in- $&in- 'i%4%i #4& $&*i% #%n-. P%'%
,,n2% '&% 'i#%*i '&n-%n &&i%n %n*ii&*i3 ($&&*i: Acetaminofen /
Paracetamol). Di$%in- &n--,n%%n #%* %n*ii&*i3" '%%* 'i-,n%3%n #%*
*%'i$i#n%4 2%n- &%$%4 '%i *%n%%n" 6#n*#n2% &ni%n.
T,+,%n &n&4i*i%n ini ,n*,3 &n-&*%,i &&3 %n*ii&*i3 in,$% &%
&ni%n.P&n&4i*i%n ini 'i4%3,3%n *&%'% 80 &3# &n6i* +%n*%n -%4, Swiss
Webster '&n-%n &%* %'%n $&3i*% 9 -%. M&n6i* 'i3&4##33%n $&6%% %6%3
'%4% 4i% 3&4##3 %$in-%$in- *&'ii '%i &n% &3# &n6i* $&&4, 'i
in',3$i '&n-%n ;%3$in 6%%3 2%n- &&i &&3 '&% *&%'% &n6i*.
S&*&4% < +% 'i in',3$i $,, 'i ,3, 3&%4i. K&4##3 I" II" '%n III %'%4%
3&4##3 %%n ,+i in,$% &% &ni%n (IHM) '#$i$ !"9=" 18=" '%n !=.
S&'%n-3%n 3&4##3 I> %'%4% 3&4##3 3#n*#4 n&-%*i &n--,n%3% %?,%'&$*
'%n 3&4##3 I> $&%-%i 3#n*#4 #$i*i '&n-%n %%$&*%#4.
D%*% 2%n- 'i ,3, %'%4% &n,,n%n $,, *,, &n6i* $&$,'% 'i
in',3$i ;%3$in 6%%3. An%4i$i$ '%*% &n--,n%3%n ANA>A $%*, %%" 2%n-
%%i4% *&'%%* &&'%%n 'i4%n+,*3%n '&n-%n ,+i T,3&2 HSD '&n-%n @ 0"09"
3&%3n%%n '&n-%n ni4%i 0"09.
H%$i4 &n&4i*i%n &n,n+,33%n %*%%*% &n,,n%n $,, *,, &n6i* %'%
3&4##3 IHM !"9=" IHM 18=" '%n IHM != &i4i3i &&3 %n*ii&*i3.
K&$i,4%n %'%4% &&i%n in,$% &% &ni%n &&&3 $&6%%
$i-nii3%n %'% &n,,n%n $,, *,, &n6i* -%4, S/i$$ W&$*& +%n*%n.
K%*% 3,n6i : An*ii&*i3" M&ni%n
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ABSTRACT
ANTIPYRETIC EFFECT OF MENIRAN (Phyllanthus niruri Linn.)INFUSION TO MALE MICE STRAIN SWISS WEBSTER
F&n*2 D. B%,$" 01 T,*# I : R#$n%&ni" '%." A*
T,*# II : D+,$&n%" '."AIF
Fever is the most common symptoms experienced by each people.
In most cases fever were treated with the provision of antipyretics (such as
Acetaminophen / Paracetamol!. "esides the use of antipyretic dru#s$ can be used
traditional medicine derived from plants$ for example meniran.
%he purpose of this research is to find out the effect of antipyretic of
meniran infusion.%his research was conducted to &' male mice strain Swiss Webster with
avera#e wei#ht ) #ram. %he mice were divided by five #roups randomly with
containin# six mice each #roup. %he #roupin# was done before inducted by
*easles vaccine that #ave fever effect to the mice. After + hours induction$ the
temperature was measured a#ain. ,roup I$ II$ and III is the tested #roups that
were #iven I-* $)$ 0&$ and +. While #roup I1 is the ne#ative control
usin# a2uadest$ and #roup 1 is the positif control usin# paracetamol.
%he data measured is the reduction of body temperature of mice after the
induction of measles vaccine. 3ata analysis usin# one way A451A$ that if there
are differences continued by %u6ey -S3 test with 7 8 '.')$ si#nificance with p
value 9 '.').
%he results show an avera#e reduction body temperature of mice at the
I-* #roup $)$ 0& I-* and I-* has antipiretyc effect.
%he conclusion is the provision of meniran infusion has si#nificant effect
to reduction body temperature of Swiss Webster strain male mice.
:eyword Antipyretic$ *eniran
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KATA PENGANTAR
P,+i '%n $2,3, 3&%'% T,%n Y&$,$ Ki$*,$" 2%n- *&4% &&3%*i '%n
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&n2&4&$%i3%n K%2% T,4i$ I4i% ini.
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&%-%i i%3. Un*,3 i*, &n,4i$ &n-,6%3%n %n2%3 *&i% 3%$i 3&%'% :
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/%3*," *&n%-%" '%n i3i%n $&4%% &iin- &n,4i$ '%4%
&n2&4&$%i%n K%2% T,4i$ I4i% ini.
. D+,$&n%" '" AIF $&4%3, &iin- II 2%n- *&4% &$&'i% &4,%n-3%n
/%3*," *&n%-%" '%n i3i%n $&4%% &iin- &n,4i$ '%4%
&n2&4&$%i%n K%2% T,4i$ I4i% ini.
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'%4% &n%*%4%3$%n%%n &n&4i*i%n.
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B%n',n-" F&,%i 01
P&n,4i$
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DAFTAR ISI
H%4%%n
JUDUL............................................................................................................ i
LEMBAR PERSETUJUAN........................................................................... ii
SURAT PERNYATAAN...............................................................................
ABSTRAK......................................................................................................
A"S%;A
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8.< M&*#'& An%4i$i$..................................................................................... 7
8.9 Hi#*&$i$ S*%*i$*i3..................................................................................... 7
8.! A$&3 P&n&4i*i%n........................................................................................
BAB I> HASIL DAN PEMBAHASAN.......................................................
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T%&4
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G%% . >%3$in C%%3..........................................................
G%% .10 M&ni%n (Phyllanthus niruri L)................................................
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DAFTAR GRAFIK
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DAFTAR LAMPIRAN
L%i%n 1 P&i*,n-%n D#$i$..............................
L%i%n P#$&', P&,%*%n In,$% ....................................................
L%i%n 8 H%$i4 U+i * T&$*................................
L%i%n < H%$i4 ,+iA451A$%*, %% '%n ,+i HSD ....................................
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