Cyclosporin dapat meningkatkan sel goblet oleh karena:Cyclosporin sbg antiinflamasi mempunyai pengaruh membantu memperbaiki sel goblet conjungtivaMenurunkan turnover epithelial sel gobletMengurangi inflamasi permukaan ocular shg dapat berpengaruh pada aktifitas proliferasi epitel dan memperbaiki integritas epitel permukaan ocularMencegah apoptosis patologis

I typically pretreat the patient with cyclosporine for 1-3 months to reduce the concentration of inflammatory mediators in the tears.Because the hormonal changes of menopause specifically affect the meibomian glands that produce the lipid layer of the tear film as well as lacrimal glands that produce aqueous tears, I recommend a lipid-restorative tear like Soothe, especially for patients with mild disease. The lipid helps retain tears and prevent ocular surface damage.

For patients with more advanced disease, adding an anti-inflammatory drug can be very helpful. A corticosteroid can bring the inflammatory response under control quickly, and topical cyclosporine can suppress the T-cell-mediated portion of the inflammatory response, allowing many patients to produce healthier tears and gain long-term relief.