fisiologi pembentukan urine

7/26/2019 Fisiologi Pembentukan Urine

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F I S I O L O G IF I S I O L O G I14 Desember 200714 Desember 2007

STIKES MITRA RIA HUSADASTIKES MITRA RIA HUSADA


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FISIOLOGI SISTEM URINARIAFISIOLOGI SISTEM URINARIA

Fungsi Gin!"Fungsi Gin!" #enge"u!r!n $!% sis! &rg!ni'(#enge"u!r!n $!% sis! &rg!ni'( #eng!%ur!n '&nsen%r!si i&n)i&n *en%ing(#eng!%ur!n '&nsen%r!si i&n)i&n *en%ing( #eng!%ur!n 'eseimb!ng!n !s!m b!s! %ubu+(#eng!%ur!n 'eseimb!ng!n !s!m b!s! %ubu+( #eng!%ur!n *r&,u'si se" ,!r!+ mer!+(#eng!%ur!n *r&,u'si se" ,!r!+ mer!+( #eng!%ur!n %e'!n!n ,!r!+(#eng!%ur!n %e'!n!n ,!r!+(

#engen,!"i!n %erb!%!s *!,! '!,!r g"u'&s!#engen,!"i!n %erb!%!s *!,! '!,!r g"u'&s!,!n !s!m !min& ,!r!+(,!n !s!m !min& ,!r!+(

#enge"u!r!n $!%)$!% ber!-un(#enge"u!r!n $!%)$!% ber!-un(


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#EM.ENTUKAN URIN#EM.ENTUKAN URIN

Di,!"!m '!*i"er g"&meru"er/ ,!r!+ ,is!ring &"e+ ,in,ing2Di,!"!m '!*i"er g"&meru"er/ ,!r!+ ,is!ring &"e+ ,in,ing2

en,&%e" '!*i"er g"&meru"er(en,&%e" '!*i"er g"&meru"er(

!ng %ers!ring 'e"u!r m!su' 'e '!*su" .&m!n !,!"!+!ng %ers!ring 'e"u!r m!su' 'e '!*su" .&m!n !,!"!+

!ir ,!n $!% %er"!ru% ,eng!n ber!% m&"e'u" ren,!+ se*er%i!ir ,!n $!% %er"!ru% ,eng!n ber!% m&"e'u" ren,!+ se*er%i

g"u'&s!/ "/ N!/ K/ F&s3!%/ Ure!/ !s!m ur!%/ ,!ng"u'&s!/ "/ N!/ K/ F&s3!%/ Ure!/ !s!m ur!%/ ,!n

're!%in!n('re!%in!n(

#en!ring!n ini ,imung'in'!n %er!,i ,i '!*i"er#en!ring!n ini ,imung'in'!n %er!,i ,i '!*i"er

g"&meru"er '!ren!5g"&meru"er '!ren!5

Din,ing '!*i"er g"&meru"er "ebi+ *erme!be" ,!ri*!,!Din,ing '!*i"er g"&meru"er "ebi+ *erme!be" ,!ri*!,!

,in,ing '!*i"er ,i %em*!% "!in(,in,ing '!*i"er ,i %em*!% "!in( Te'!n!n ,!r!+ ,!"!m '!*i"er g"&meru"er "ebi+ %inggiTe'!n!n ,!r!+ ,!"!m '!*i"er g"&meru"er "ebi+ %inggi

,ib!n,ing ,i %em*!% "!in(,ib!n,ing ,i %em*!% "!in(


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Me'!nisme *en!ring!n5Me'!nisme *en!ring!n5 K!ren! !,! ,!! ,&r&ng 6!i%u %e'!n!nK!ren! !,! ,!! ,&r&ng 6!i%u %e'!n!n

+i,r&s%!%i' ,!r!+ !ng men,&r&ng $!%2+i,r&s%!%i' ,!r!+ !ng men,&r&ng $!%2

%ers!ring 'e"u!r ,!ri '!*i"er g"&meru"er m!su'%ers!ring 'e"u!r ,!ri '!*i"er g"&meru"er m!su'

'e '!*su" .&m!n('e '!*su" .&m!n( D!! ,&r&ng i%u mem*er&"e+ *er"!!n!nD!! ,&r&ng i%u mem*er&"e+ *er"!!n!n

,!ri5,!ri5

8 Te'!n!n +i,r&s%!%i' ,!"!m '!*su" .&m!n(Te'!n!n +i,r&s%!%i' ,!"!m '!*su" .&m!n(8 Te'!n!n &sm&%i' '&"&i, *"!sm! ,!ri '!*i"erTe'!n!n &sm&%i' '&"&i, *"!sm! ,!ri '!*i"er

g"&meru"er(g"&meru"er(


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9!"!u*un !,! *er"!!n!n/ %e%!*i9!"!u*un !,! *er"!!n!n/ %e%!*i

*en!ring!n %e%!* ber!"!n '!ren!*en!ring!n %e%!* ber!"!n '!ren!Te'!n!n +i,r&s%!%i' ,!"!m '!*i"erTe'!n!n +i,r&s%!%i' ,!"!m '!*i"erg"&meru"er "ebi+ bes!r ,!ri*!,! %e'!n!ng"&meru"er "ebi+ bes!r ,!ri*!,! %e'!n!n+i,r&s%!%i' '!*su" .&m!n m!u*un+i,r&s%!%i' '!*su" .&m!n m!u*un

%e'!n!n &sm&%i' '&"&i, *"!sm! '!*i"er%e'!n!n &sm&%i' '&"&i, *"!sm! '!*i"erg"&meru"er(g"&meru"er(

Se"isi+ %e'!n!n %ersebu% ,isebu% Te'!n!nSe"isi+ %e'!n!n %ersebu% ,isebu% Te'!n!n

Fi"%r!si E3e'%i3(Fi"%r!si E3e'%i3( TFE : Te' Hi, g"&meru"er ; 6Te' Hi,TFE : Te' Hi, g"&meru"er ; 6Te' Hi,

'!*su" < Te' &sm g"&meru"er'!*su" < Te' &sm g"&meru"er


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=!% !ng %ers!ring 'e"u!r ,isebu% 3i"%r!%(=!% !ng %ers!ring 'e"u!r ,isebu% 3i"%r!%(

>um"!+ 3i"%r!% !ng %erben%u' ,!"!m s!%u>um"!+ 3i"%r!% !ng %erben%u' ,!"!m s!%umeni% ,isebu% L!u Fi"%r!si G"&meru"ermeni% ,isebu% L!u Fi"%r!si G"&meru"er6G"&meru"er Fi"%r!%i&n R!%e 6GFR(6G"&meru"er Fi"%r!%i&n R!%e 6GFR(

Se%e"!+ 3i"%r!% m!su' 'e '!*su" .&m!n/Se%e"!+ 3i"%r!% m!su' 'e '!*su" .&m!n/

'emu,i!n m!su' 'e %ubu"us('emu,i!n m!su' 'e %ubu"us( Re!bs&rsi(Re!bs&rsi(

Di ,!"!m %ubu"us ini %er!,i re!bs&rbsi ,!nDi ,!"!m %ubu"us ini %er!,i re!bs&rbsi ,!n

se'resi i&n)i&n ,!n $!%)$!% "!in(se'resi i&n)i&n ,!n $!%)$!% "!in( Re!bs&rbsi ini me"!"ui me'!nisme ,i3usi/Re!bs&rbsi ini me"!"ui me'!nisme ,i3usi/

&sm&se ,!n %r!n*&r !'%i3(&sm&se ,!n %r!n*&r !'%i3(


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Di ,!"!m %ubu"us '&n%&r%us *r&'sim!" %er!,iDi ,!"!m %ubu"us '&n%&r%us *r&'sim!" %er!,ire!bs&rbsi ?@ N!/ "/ ,!n !ir( Se,!ng'!nre!bs&rbsi ?@ N!/ "/ ,!n !ir( Se,!ng'!ng"u'&s!/ ,!n !s!m !min& ,ire!bs&rbsi 100g"u'&s!/ ,!n !s!m !min& ,ire!bs&rbsi 100((

Ure! ug! meng!"!mi re!bs&rbsi/ %e%!*i +!n!Ure! ug! meng!"!mi re!bs&rbsi/ %e%!*i +!n!@0 (@0 (

I&n "!in se*er%i K/ !/ 3&s3!%/ ,"" ug!I&n "!in se*er%i K/ !/ 3&s3!%/ ,"" ug!,ire!bs&rbsi(,ire!bs&rbsi(

Se'resi(Se'resi( Di s!m*ing re!bs&rbsi/ %er!,i ug! se'resi ,iDi s!m*ing re!bs&rbsi/ %er!,i ug! se'resi ,i

%ubu"us '&n%&r%us ,is%!" ,!n %ubu"us%ubu"us '&n%&r%us ,is%!" ,!n %ubu"us*engum*u"(*engum*u"(


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H/ K/ Am&nium/ Kre!%inin/ &b!%)&b!%!n/H/ K/ Am&nium/ Kre!%inin/ &b!%)&b!%!n/

,ise'resi ,i %ubu"us '&n%&r%us ,is%!" ,!n,ise'resi ,i %ubu"us '&n%&r%us ,is%!" ,!n%ubu"us *engum*u"(%ubu"us *engum*u"( Se'resi ini *en%ing un%u' men!g! *H ,!nSe'resi ini *en%ing un%u' men!g! *H ,!n

'eseimb!ng!n !s!m b!s! %ubu+ ,!n'eseimb!ng!n !s!m b!s! %ubu+ ,!n

*enge"u!r!n $!%)$!% r!-un(*enge"u!r!n $!%)$!% r!-un(Me'!nisme #engen-er!n(Me'!nisme #engen-er!n(

Di*eng!ru+i &"e+ ADH 6An%i ,iure%i' H&rm&nDi*eng!ru+i &"e+ ADH 6An%i ,iure%i' H&rm&n,!n !",&s%er&n(,!n !",&s%er&n(

ADH ,!n !",&s%er&n meneb!b'!nADH ,!n !",&s%er&n meneb!b'!nmening'!%n! *erme!bi"i%!s %ubu"us se+ingg!mening'!%n! *erme!bi"i%!s %ubu"us se+ingg!!'!n mening'!%'!n re!bs&rbsi !ir!'!n mening'!%'!n re!bs&rbsi !ir


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H!" ini !'!n meneb!b'!n B&"ume urinH!" ini !'!n meneb!b'!n B&"ume urin

menurun(menurun(

A*!bi"! ADH um"!+n! menurun/ m!'!A*!bi"! ADH um"!+n! menurun/ m!'!

re!bs&rbsi !ir ug! menurun( A'ib!%n!re!bs&rbsi !ir ug! menurun( A'ib!%n!

um"!+ urin mening'!%(um"!+ urin mening'!%(

H!")+!" !ng meneb!b'!n ADH n!i'5H!")+!" !ng meneb!b'!n ADH n!i'58 #ening'!%!n &sm&"!"i%!s *"!sm!(#ening'!%!n &sm&"!"i%!s *"!sm!(

8 #enurun!n B&"ume ,!n %e'!n!n ,!r!+(#enurun!n B&"ume ,!n %e'!n!n ,!r!+(

H!")+!" !ng meneb!b'!n ADH %urun5H!")+!" !ng meneb!b'!n ADH %urun58 #enurun!n &sm&"!"i%!s *"!sm!(#enurun!n &sm&"!"i%!s *"!sm!(

8 #ening'!%!n B&"ume ,!n %e'!n!n ,!r!+(#ening'!%!n B&"ume ,!n %e'!n!n ,!r!+(


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Si3!% ,!n '&m*&sisi urin(Si3!% ,!n '&m*&sisi urin(

Urin mem*un!i '&m*&sisi5Urin mem*un!i '&m*&sisi5

8 =!% bu!ng!n *r&%ein mis Ureum/ 're!%inin ,!n !s!m=!% bu!ng!n *r&%ein mis Ureum/ 're!%inin ,!n !s!m

ur!%(ur!%(

8 As!m +i*ur!%/ $!% sis! ,!ri *en-ern!!n s!ur ,!nAs!m +i*ur!%/ $!% sis! ,!ri *en-ern!!n s!ur ,!n

bu!+(bu!+(

8 .!,!n 'e%&n/ $!% bu!ng ,!ri me% "em!'(.!,!n 'e%&n/ $!% bu!ng ,!ri me% "em!'(

8 E"e'%r&"i%/ N!/ "/ K/ Am&nium/ su"3!%/ 3&s3!%/ !/ Mg(E"e'%r&"i%/ N!/ "/ K/ Am&nium/ su"3!%/ 3&s3!%/ !/ Mg(

8 Me%!b&"i% +&rm&n(Me%!b&"i% +&rm&n(

8 =!% %&'sin mis me%!b&"i% &b!%/ Bi%!min/ $!% 'imi!=!% %&'sin mis me%!b&"i% &b!%/ Bi%!min/ $!% 'imi!

!sing(!sing(

8 =!% !bn&rm!"/ mis *r&%ein/ g"u'&s!/ se" ,!r!+/ 'ris%!"=!% !bn&rm!"/ mis *r&%ein/ g"u'&s!/ se" ,!r!+/ 'ris%!"

'!*ur/ ,""('!*ur/ ,""(


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Si3!% Urin5Si3!% Urin5

Urin en-er ber!rn! 'uning *u-!%/ urin 'en%!"Urin en-er ber!rn! 'uning *u-!%/ urin 'en%!"ber!rn! 'uning *e'!%/ urin b!ru erni+/ '!"!uber!rn! 'uning *e'!%/ urin b!ru erni+/ '!"!u

,i,i!m'!n !g!' "!m! men!,i 'eru+(,i,i!m'!n !g!' "!m! men!,i 'eru+(

.!un! '+!s/ '!"!u ,i,i!m'!n !'!n berb!u.!un! '+!s/ '!"!u ,i,i!m'!n !'!n berb!u

!m&ni!(!m&ni!( *H berB!ri!si 4/? ; 7/@( .i!s!n! se'i%!r C/0(*H berB!ri!si 4/? ; 7/@( .i!s!n! se'i%!r C/0(

.i"! b!n!' m!'!n *r&%ein/ urin men!,i "ebi+.i"! b!n!' m!'!n *r&%ein/ urin men!,i "ebi+

!s!m/ bi"! b!n!' m!'!n s!ur urin !'!n!s!m/ bi"! b!n!' m!'!n s!ur urin !'!nmen!,i "ebi+ b!s!(men!,i "ebi+ b!s!(

.er!% enis urin 1/001 ; 1/0@(.er!% enis urin 1/001 ; 1/0@(


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Me'!nisme ber'emi+(Me'!nisme ber'emi+(

Di*eng!ru+i &"e+ s!r!3 sim*!%is ,!nDi*eng!ru+i &"e+ s!r!3 sim*!%is ,!n*!r!sim*!%is ser%! im*u"s s!r!3 B&"un%er(*!r!sim*!%is ser%! im*u"s s!r!3 B&"un%er(

O%&% *!,! '!n,ung 'emi+ !ng menge"i"ingiO%&% *!,! '!n,ung 'emi+ !ng menge"i"ingi

!"!n 'e"u!r 'e ure%r! 6s3ing%er ure%r! in%ern!"!"!n 'e"u!r 'e ure%r! 6s3ing%er ure%r! in%ern!"

sen!n%i!s! ber'&n%r!'si men!g! su*!!sen!n%i!s! ber'&n%r!'si men!g! su*!!

"ub!ng ini %e%!* %er%u%u*( Di*eng!ru+i &"e+"ub!ng ini %e%!* %er%u%u*( Di*eng!ru+i &"e+

s!r!3 *!r!sim*!%is(s!r!3 *!r!sim*!%is(

O%&% s3ing%er ure%r! e's%ern!" %er,iri ,!ri &%&%O%&% s3ing%er ure%r! e's%ern!" %er,iri ,!ri &%&%r!ng'! !ng 'er!n! se-!r! B&"un%er(r!ng'! !ng 'er!n! se-!r! B&"un%er(


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Di ,in,ing '!n,ung 'emi+ %er,!*!% &%&% ,e%rus&rDi ,in,ing '!n,ung 'emi+ %er,!*!% &%&% ,e%rus&r!ng bi"! ber'&n%r!'si meneb!b'!n urin ,!"!m!ng bi"! ber'&n%r!'si meneb!b'!n urin ,!"!m

'!n,ung 'emi+ %er,&r&ng 'e"u!r('!n,ung 'emi+ %er,&r&ng 'e"u!r(

.i"! ,!"!m '!n,ung 'emi+ %er,!*!% urin 00 ;.i"! ,!"!m '!n,ung 'emi+ %er,!*!% urin 00 ;

400 m"/ m!'! %er!,i r!ngs!ng!n *ereg!ng!n400 m"/ m!'! %er!,i r!ngs!ng!n *ereg!ng!n

*!,! ,in,ing '!n,ung 'emi+(*!,! ,in,ing '!n,ung 'emi+(

Kemu,i!n im*u"s ini ,i'irim 'e &%!'/ se+ingg!Kemu,i!n im*u"s ini ,i'irim 'e &%!'/ se+ingg!

meneb!b'!n !,!n! im*u"s *!r!sim*!%is !ngmeneb!b'!n !,!n! im*u"s *!r!sim*!%is !ngmeneb!b'!n '&n%r!'sin! &%&% ,e%rus&r/meneb!b'!n '&n%r!'sin! &%&% ,e%rus&r/

re"!'s!si &%&% s3ing%er in%ern!" ,!n e's%ern!"(re"!'s!si &%&% s3ing%er in%ern!" ,!n e's%ern!"(


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A,! ug! me'!nisme *en-eg!+!nA,! ug! me'!nisme *en-eg!+!n

ber'emi+(ber'emi+( H!" ini ,imung'in'!n ,eng!n !,!n!H!" ini ,imung'in'!n ,eng!n !,!n!

im*u"s B&"un%er !ng meneb!b'!n bis!im*u"s B&"un%er !ng meneb!b'!n bis!

,i%un,!n! '&n%r!'si &%&% ,e%rus&r ,!n,i%un,!n! '&n%r!'si &%&% ,e%rus&r ,!nre"!'s!sin! &%&% s3ing%er(re"!'s!sin! &%&% s3ing%er(

S!m*!i umur 1? bu"!n/ im*u"s B&"un%er iniS!m*!i umur 1? bu"!n/ im*u"s B&"un%er ini

be"um be'er! ,eng!n b!i'(be"um be'er! ,eng!n b!i'(

fisiologi pembentukan urine

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