farmakoterapi (sdh)
TRANSCRIPT
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PharmacotherapyPharmacotherapy
Dr. R. Setiaji, M.ScDr. R. Setiaji, M.Sc
Dept. of PharmacologyDept. of PharmacologyHasanuddin UniversityHasanuddin University
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Topics of discussionTopics of discussion
Guide line of rationalGuide line of rational
pharmacotherapypharmacotherapy
Source of informationSource of information mplementation pharmacotherapy inmplementation pharmacotherapy in
immunologic disorders !"ssignment#immunologic disorders !"ssignment#
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Problem and DiagnosisProblem and Diagnosis
$ollo% previous lecture$ollo% previous lecture
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Choose TreatmentChoose Treatment
Determine &rst choice treatmentDetermine &rst choice treatment Give adviceGive advice
'reat %ithout drug'reat %ithout drug
'reat %ith drug( P)drug'reat %ith drug( P)drug Refer for treatmentRefer for treatment
*om+ination*om+ination
*hec suita+ility for the patients*hec suita+ility for the patients
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P-drugP-drug
Personal drug choices from all drugsPersonal drug choices from all drugs
availa+leavaila+le
Practical, avoid repeated searchesPractical, avoid repeated searches
Priority choice for certainPriority choice for certain
indicationsindications
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How to select P-drugsHow to select P-drugs
Specify diagnosisSpecify diagnosis De&ne therapeutic o+jectiveDe&ne therapeutic o+jective Mae inventory of groups. Group-,Group etcMae inventory of groups. Group-,Group etc *ompare according to criteria*ompare according to criteria
/0icacy/0icacy safetysafety suita+litysuita+lity costcost Group-Group-
GroupGroup *hoose a group*hoose a group Group 1Group 1
*hoose a P)drug*hoose a P)drug /0icacy/0icacy safetysafety suita+litysuita+lity costcost
Group 12Group 12 Drug-Drug-
DrugDrug Drug3Drug3
"ctive su+stance"ctive su+stance 444..444.. Dosage formDosage form 44444444 Dosage scheduleDosage schedule 44444444 DurationDuration 44444444
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Active substanceActive substance
PharmacodynamicPharmacodynamic /0ect/0ect
Side e0ectSide e0ect
PharmacoineticPharmacoinetic
PosologiPosologi
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Check suitabilty of P-Check suitabilty of P-
DrugDrug"ctive su+stance"ctive su+stance
DosageDosage
ScheduleSchedule DurationDuration
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Start TreatmentStart Treatment
5rite prescription5rite prescription
Give information, instruction andGive information, instruction and
%arning%arning
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onitor Treatmentonitor Treatment
MonitorMonitor
StopStop
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DiagnosisDiagnosis
Main symptom(erythematous pla6ueMain symptom(erythematous pla6ue
7ther data(7ther data(
"t %rist"t %rist 5arm5arm
tchytchy
Painless on pressurePainless on pressure
Relapse after %ashingRelapse after %ashing
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DDDD MainMaincomplaicomplai
ntnt
7ther7therdatadata
7ther7therdatadata
DataDatacon&rcon&r
mm"" 11
88
**
Find Possible diagnosis
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DDDD MainMaincomplaicomplai
ntnt
7ther7therdatadata
7ther7therdatadata
DataDatacon&rcon&r
mm"" 11
88
**
Mechanism?
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Mechanism?
Group of drug
Active substance
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!rythematous!rythematous
Pla"uePla"ue
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Table 55-1. Descriptions of Primary Skin LesionsTable 55-1. Descriptions of Primary Skin Lesions
Macule: A flat, colored lesion,
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DDDD pla6upla6uee
inter&ninter&ngerger
itchitch con&rmcon&rmationation
"topy D"topy D
psoariasispsoariasis
*ontact*ontactDD
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!ach Diagnosis!ach Diagnosis
*linical feature*linical feature
9a+oratory9a+oratory
'reatment'reatment"natomy:Histology, Physiology,"natomy:Histology, Physiology,
Pathology, other related theoryPathology, other related theory
Hypersensitive typeHypersensitive type /tc/tc
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How to select P-drugsHow to select P-drugs
Specify diagnosisSpecify diagnosis De&ne therapeutic o+jectiveDe&ne therapeutic o+jective Mae inventory of groups. Group-,Group etcMae inventory of groups. Group-,Group etc *ompare according to criteria*ompare according to criteria
/0icacy/0icacy safetysafety suita+litysuita+lity costcost Group-Group-
GroupGroup *hoose a group*hoose a group Group 1Group 1
*hoose a P)drug*hoose a P)drug /0icacy/0icacy safetysafety suita+litysuita+lity costcost
Group 12Group 12 Drug-Drug-
DrugDrug Drug3Drug3 "ctive su+stance"ctive su+stance 444..444.. Dosage formDosage form 44444444 Dosage scheduleDosage schedule 44444444 DurationDuration 44444444
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Chronic #unningChronic #unning
$ose$ose
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DDDD rhinorerhinore PostPostnasalnasaldripdrip
"topic"topichystorhystor
yy
*on&rm*on&rme;aminae;aminationtion
R. "lergyR. "lergy ;; ;; ;;
R vasomotorR vasomotor ;; ;;
PolypPolyp ;;
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#eevaluate !ach#eevaluate !ach
DiagnosisDiagnosis *linical feature*linical feature
Hypersensitive MechanismHypersensitive Mechanism
9a+oratory9a+oratory 'reatment'reatment
PrognosisPrognosis
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AssignmentAssignment
Mae list of drug groups for(Mae list of drug groups for( "llergic rhinitis"llergic rhinitis
"llergical *ontact dermatitis"llergical *ontact dermatitis
"topy Dermatitis"topy Dermatitis "llergic asthma +ronchiale"llergic asthma +ronchiale
9ist of active su+stance, dosage, schedule,9ist of active su+stance, dosage, schedule,
duration, side e0ects and contraduration, side e0ects and contra
indications.indications.
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ClueClue
7pen your