farmakoterapi (sdh)

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    PharmacotherapyPharmacotherapy

    Dr. R. Setiaji, M.ScDr. R. Setiaji, M.Sc

    Dept. of PharmacologyDept. of PharmacologyHasanuddin UniversityHasanuddin University

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    Topics of discussionTopics of discussion

    Guide line of rationalGuide line of rational

    pharmacotherapypharmacotherapy

    Source of informationSource of information mplementation pharmacotherapy inmplementation pharmacotherapy in

    immunologic disorders !"ssignment#immunologic disorders !"ssignment#

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    Problem and DiagnosisProblem and Diagnosis

    $ollo% previous lecture$ollo% previous lecture

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    Choose TreatmentChoose Treatment

    Determine &rst choice treatmentDetermine &rst choice treatment Give adviceGive advice

    'reat %ithout drug'reat %ithout drug

    'reat %ith drug( P)drug'reat %ith drug( P)drug Refer for treatmentRefer for treatment

    *om+ination*om+ination

    *hec suita+ility for the patients*hec suita+ility for the patients

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    P-drugP-drug

    Personal drug choices from all drugsPersonal drug choices from all drugs

    availa+leavaila+le

    Practical, avoid repeated searchesPractical, avoid repeated searches

    Priority choice for certainPriority choice for certain

    indicationsindications

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    How to select P-drugsHow to select P-drugs

    Specify diagnosisSpecify diagnosis De&ne therapeutic o+jectiveDe&ne therapeutic o+jective Mae inventory of groups. Group-,Group etcMae inventory of groups. Group-,Group etc *ompare according to criteria*ompare according to criteria

    /0icacy/0icacy safetysafety suita+litysuita+lity costcost Group-Group-

    GroupGroup *hoose a group*hoose a group Group 1Group 1

    *hoose a P)drug*hoose a P)drug /0icacy/0icacy safetysafety suita+litysuita+lity costcost

    Group 12Group 12 Drug-Drug-

    DrugDrug Drug3Drug3

    "ctive su+stance"ctive su+stance 444..444.. Dosage formDosage form 44444444 Dosage scheduleDosage schedule 44444444 DurationDuration 44444444

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    Active substanceActive substance

    PharmacodynamicPharmacodynamic /0ect/0ect

    Side e0ectSide e0ect

    PharmacoineticPharmacoinetic

    PosologiPosologi

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    Check suitabilty of P-Check suitabilty of P-

    DrugDrug"ctive su+stance"ctive su+stance

    DosageDosage

    ScheduleSchedule DurationDuration

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    Start TreatmentStart Treatment

    5rite prescription5rite prescription

    Give information, instruction andGive information, instruction and

    %arning%arning

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    onitor Treatmentonitor Treatment

    MonitorMonitor

    StopStop

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    DiagnosisDiagnosis

    Main symptom(erythematous pla6ueMain symptom(erythematous pla6ue

    7ther data(7ther data(

    "t %rist"t %rist 5arm5arm

    tchytchy

    Painless on pressurePainless on pressure

    Relapse after %ashingRelapse after %ashing

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    DDDD MainMaincomplaicomplai

    ntnt

    7ther7therdatadata

    7ther7therdatadata

    DataDatacon&rcon&r

    mm"" 11

    88

    **

    Find Possible diagnosis

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    DDDD MainMaincomplaicomplai

    ntnt

    7ther7therdatadata

    7ther7therdatadata

    DataDatacon&rcon&r

    mm"" 11

    88

    **

    Mechanism?

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    Mechanism?

    Group of drug

    Active substance

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    !rythematous!rythematous

    Pla"uePla"ue

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    Table 55-1. Descriptions of Primary Skin LesionsTable 55-1. Descriptions of Primary Skin Lesions

    Macule: A flat, colored lesion,

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    DDDD pla6upla6uee

    inter&ninter&ngerger

    itchitch con&rmcon&rmationation

    "topy D"topy D

    psoariasispsoariasis

    *ontact*ontactDD

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    !ach Diagnosis!ach Diagnosis

    *linical feature*linical feature

    9a+oratory9a+oratory

    'reatment'reatment"natomy:Histology, Physiology,"natomy:Histology, Physiology,

    Pathology, other related theoryPathology, other related theory

    Hypersensitive typeHypersensitive type /tc/tc

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    How to select P-drugsHow to select P-drugs

    Specify diagnosisSpecify diagnosis De&ne therapeutic o+jectiveDe&ne therapeutic o+jective Mae inventory of groups. Group-,Group etcMae inventory of groups. Group-,Group etc *ompare according to criteria*ompare according to criteria

    /0icacy/0icacy safetysafety suita+litysuita+lity costcost Group-Group-

    GroupGroup *hoose a group*hoose a group Group 1Group 1

    *hoose a P)drug*hoose a P)drug /0icacy/0icacy safetysafety suita+litysuita+lity costcost

    Group 12Group 12 Drug-Drug-

    DrugDrug Drug3Drug3 "ctive su+stance"ctive su+stance 444..444.. Dosage formDosage form 44444444 Dosage scheduleDosage schedule 44444444 DurationDuration 44444444

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    Chronic #unningChronic #unning

    $ose$ose

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    DDDD rhinorerhinore PostPostnasalnasaldripdrip

    "topic"topichystorhystor

    yy

    *on&rm*on&rme;aminae;aminationtion

    R. "lergyR. "lergy ;; ;; ;;

    R vasomotorR vasomotor ;; ;;

    PolypPolyp ;;

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    #eevaluate !ach#eevaluate !ach

    DiagnosisDiagnosis *linical feature*linical feature

    Hypersensitive MechanismHypersensitive Mechanism

    9a+oratory9a+oratory 'reatment'reatment

    PrognosisPrognosis

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    AssignmentAssignment

    Mae list of drug groups for(Mae list of drug groups for( "llergic rhinitis"llergic rhinitis

    "llergical *ontact dermatitis"llergical *ontact dermatitis

    "topy Dermatitis"topy Dermatitis "llergic asthma +ronchiale"llergic asthma +ronchiale

    9ist of active su+stance, dosage, schedule,9ist of active su+stance, dosage, schedule,

    duration, side e0ects and contraduration, side e0ects and contra

    indications.indications.

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    ClueClue

    7pen your