farmakoekonomi1
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FARMAKOEKONOMI
VITIS VINI FERA R.U
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Komposisi nilai:
30 % tugas terstruktur
30 % ujian mid30 % ujian akhir
10keaktifan?
Bobot nilai: A: 80,00; B: 66,00-79,99;C: 56,00-65,99; D: 46,00-55,99; E: 46,00
Kontrak Pembelajaran
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Materi Perkuliahan dan Tugas
Kompetensi Mata Kuliah: Mahasiswa mampu menjelaskananalisis farmakoekonomi untuk membandingkan pelayanankesehatan yang paling efektif
Pendahuluan: Pentingnya mata kuliah farmakoekonomi,
Prinsip Dasar Farmakoekonomi Analisis Farmakoekonomi (cost minimization analysis/CMA,
cost effectiveness analysis/CEA, cost utility analysisi/CUA, costbenefit analysis/CBA)
Pengukuran Kualitas Hidup Dalam Evaluasi Obat
Analisis Keputusan dan Evaluasi Farmakoekonomi
Studi Kasus
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Pendahuluan
Apoteker Sebagai Bagian Dari Sistem Pelayanan Kesehatan
DOKTER
PASIEN
PERAWAT
AHLI GIZIAPOTEKER
PROFESIONAL
LAINNYA
PELAYANAN
MEDIS
ASUHANKEPERAWATAN
PELAYANAN
GIZI
PELAYANAN
FARMASI
PELAYANANKESEHATAN
LAINNYA
KONTAK
PROFESIONAL
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HEALTH
CARE
OUTCOME
HUMANISTICCLINICAL ECONOMIC
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Economics: science of scarcity and choice
RESOURCES CHOICES
NEEDS
WANTS
PRIORITY
SUPPLY
DEMANDS
we want to make the
best use of them.
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If you have only 15,000 Rp.
You have choices of lunch,
either or
How do you make decision?
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As a pharmacist at community
pharmacy
There is a child getting sick with URI upper respiratory infection.
There are choices of
or
How do you select?
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What you may concern.
Does it work (symptom vs efficacy)?
What is side effect?
What would the patient feel (taste, compliance)?
How much does it cost (concerning on patients
economic status/ affordability)?
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Your Job : As a hospital pharmacist,you have to provide evidence
for hospital administrative board
to incorporate COX-2 for osteoarthritisinto hospital formulary.
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Factor NSAID COX-2
Efficacy higher lower
Side effect
- gastrointestinal lower higher
- cardiovascular lower higher
Drug cost/ 3 months lower higher
Factor NSAID COX-2
Efficacy lower higher
Side effect
- gastrointestinal higher lower
- cardiovascular higher lower
Drug cost/ 3 months higher lower
IF; scenario A. Which one do you select?
IF; scenario B. Which one do you select?
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Factor NSAID COX-2
Efficacy
lower
higher
Side effect
- gastrointestinal higher lower
- cardiovascular higher/ lower lower/ higher
Drug cost/ 3 months
lower
higher
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Preliminary review
Which one is better? NSAID or COX-2
Which one is cheaper? NSAID or COX-2
Which one will you select? NSAID or COX-2
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In sum
We have limited money/ resources.
We have choices of how to use the money.
When we use money for one choice, we lose
opportunity to use for another choice.
We have to make decision on choosing for a moreworthwhile of money used.
Outcomes of choices are multiple ones. We need a method to combine outcomes before
comparing between the choices.
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Economic Burden
to the Society
Obat Yang Rasional: Safe, Effective,Acceptable PENINGKATAN
KESEJAHTERAAN PASIEN
ACCESSIBLE
DISEASE BURDEN
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Reeder CE. Overview of pharmacoeconomics and pharmaceutical outcomes
evaluations. Am. J. Health Syst. Pharm. 1995;52(suppl_4):S5-8.
Pharmacoeconomics:
Pharmacoeconomics may be defined as balancing the
costwith the consequences (outcomes) ofpharmaceutical therapies and services.
As a type of outcomes evaluation, pharmacoeconomics
looks beyond just the direct cost of a pharmaceutical by
including its impact on total health resource utilizationand costs.
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Health economics is a discipline that analyses
the economic aspects of health and healthcareand that usually focuses on the costs
(inputs) and the consequences (outcomes) of
health care interventions using methods and
theories from economics and medicine.
Berger et al 2003.
Economic evaluation is the comparative
analysis of alternative courses of action in
terms of both their costs and consequences.
Drummond et al 2005.
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EE_TP_theory.pptx
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Why study Pharmacoeconomics?
Health Expenditures as a % of GDP by Country
0.02.0
4.0
6.0
8.0
10.0
12.014.0
16.0
18.0
1970
1975
1980
1985
1990
1995
2000
2005
Year
%G
DP
Canada
France
Germany
Japan
United Kingdom
United States
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But when it comes to outcomes
Life Expectancy at Birth by Country
60
63
66
69
72
75
78
81
84
1961
1966
1971
1976
1981
1986
1991
1996
2001
2004
YEAR
YearsofLife CanadaFrance
Germany
Japan
UK
US
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So
What are we doing wrong?
And how can we improve ourperformance?
by spending less
getting better outcomes
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Pharmacoeconomics allows us
to compare the economic resources consumed
(inputs) to produce the health and economic
consequences of products or services
(outcomes).
INPUTS OUTCOMES
Economic Health and EconomicResources Consequences
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Patient
Outcomes
Clinical
Economic
HumanisticPathogens
Socio-economic factors
Technology
Healthcare facilities
Health financing
Outcomes in health care (ECHO model)
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Outcomesof Health Care
Clinical outcomes;mortality, morbidity, disability, clinical end points e.g.
blood pressure, serum glucose concentrations.
Humanistic outcomes;
effects on physical, social, and emotional well-being e.g.
patient satisfaction, QALYs (Quality-adjusted life years).
Economic outcomes;
impact on total health resource utilization and cost e.g.savings (change) on treatment cost due to clinical
pharmacy services.
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Economic evaluation (EE)
The comparative analysis of alternative
courses of action in terms of both their costs
and consequences.
Choice
Program A
Program B
Consequences A
Consequences B
Cost A
Cost B
EE_TP_theory.pptx
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25
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Principles of EE
CostsoftheoptionEffectivenessoftheoption
Lower
Higher
LowerHigher
EE
EE(rare case)
Accept
Reject
EE_TP_theory.pptx
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2. Identify the perspective
that is, who will be utilizing the information to
make whatdecisions.
This will guide you in choosing the relevant
costs and benefits.
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Perspectives
1. Patient
2. Health Practitioner
3. Hospitals or Hospital systems
4. Third-Party payers
5. Societal
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Patient Perspective
Examples of costs that directly affectthe patient include:
Out-of-Pocket costs
lost income transportation
Relevant Consequences are: Therapeutic effectiveness Adverse events Quality of Life (QOL)
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Health Practitioner
Costs to physicians may include:
Hospitalization
Pharmacy
Personnel
Supplies
Consequences of interest are:
Therapeutic effectiveness
Adverse events
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Hospitals
Costs include:
Hospital stay costs
Treatment of adverse events & complications
Consequences of interest:
Therapeutic effectiveness
Adverse events
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Third-Party Payer
Costs of care incurred for covered serviceswhich may include:
Hospitalization
Pharmacy
Nursing home care
Consequences of interest None
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Societal
All possible costs including lost productivity
All possible consequences including QoL, & lifeyears.
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Cost factors are becoming more
important
From whose perspective?
Health provider?
Patient?
Societal (masyarakat)?
Payer?
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Biaya (cost) didefinisikan sebagai besarnya
sumber daya (resources) yang dikonsumsi
Biaya produk atau pelayanan merupakan nilai
moneter dari sumber daya yang dikonsumsi
dalam menghasilkan barang atau jasa
Sumber daya antara lain: sdm, sarana prasarana,
gedung
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Macam-macam biaya
Biaya Langsung (Direct Cost)
Biaya Tak Langsung (Indirect Cost)
Biaya Tak Teraba (Intangible Cost)
Biaya Tetap (Fixed Cost) Biaya Tidak Tetap (Variable Cost)
Biaya rata-rata (Average Cost)
Biaya marjinal (Marginal Cost)
Cost of illness Cost of therapy
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Quote of the day
adai membuat pohon memiliki
akar yang lebih dalam dan kuat
(Dolly Parton, Singer, Amerika)