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    FARMAKOEKONOMI

    VITIS VINI FERA R.U

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    Komposisi nilai:

    30 % tugas terstruktur

    30 % ujian mid30 % ujian akhir

    10keaktifan?

    Bobot nilai: A: 80,00; B: 66,00-79,99;C: 56,00-65,99; D: 46,00-55,99; E: 46,00

    Kontrak Pembelajaran

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    Materi Perkuliahan dan Tugas

    Kompetensi Mata Kuliah: Mahasiswa mampu menjelaskananalisis farmakoekonomi untuk membandingkan pelayanankesehatan yang paling efektif

    Pendahuluan: Pentingnya mata kuliah farmakoekonomi,

    Prinsip Dasar Farmakoekonomi Analisis Farmakoekonomi (cost minimization analysis/CMA,

    cost effectiveness analysis/CEA, cost utility analysisi/CUA, costbenefit analysis/CBA)

    Pengukuran Kualitas Hidup Dalam Evaluasi Obat

    Analisis Keputusan dan Evaluasi Farmakoekonomi

    Studi Kasus

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    Pendahuluan

    Apoteker Sebagai Bagian Dari Sistem Pelayanan Kesehatan

    DOKTER

    PASIEN

    PERAWAT

    AHLI GIZIAPOTEKER

    PROFESIONAL

    LAINNYA

    PELAYANAN

    MEDIS

    ASUHANKEPERAWATAN

    PELAYANAN

    GIZI

    PELAYANAN

    FARMASI

    PELAYANANKESEHATAN

    LAINNYA

    KONTAK

    PROFESIONAL

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    HEALTH

    CARE

    OUTCOME

    HUMANISTICCLINICAL ECONOMIC

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    Economics: science of scarcity and choice

    RESOURCES CHOICES

    NEEDS

    WANTS

    PRIORITY

    SUPPLY

    DEMANDS

    we want to make the

    best use of them.

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    If you have only 15,000 Rp.

    You have choices of lunch,

    either or

    How do you make decision?

    7

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    As a pharmacist at community

    pharmacy

    There is a child getting sick with URI upper respiratory infection.

    There are choices of

    or

    How do you select?

    8

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    What you may concern.

    Does it work (symptom vs efficacy)?

    What is side effect?

    What would the patient feel (taste, compliance)?

    How much does it cost (concerning on patients

    economic status/ affordability)?

    9

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    Your Job : As a hospital pharmacist,you have to provide evidence

    for hospital administrative board

    to incorporate COX-2 for osteoarthritisinto hospital formulary.

    10

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    11

    Factor NSAID COX-2

    Efficacy higher lower

    Side effect

    - gastrointestinal lower higher

    - cardiovascular lower higher

    Drug cost/ 3 months lower higher

    Factor NSAID COX-2

    Efficacy lower higher

    Side effect

    - gastrointestinal higher lower

    - cardiovascular higher lower

    Drug cost/ 3 months higher lower

    IF; scenario A. Which one do you select?

    IF; scenario B. Which one do you select?

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    Factor NSAID COX-2

    Efficacy

    lower

    higher

    Side effect

    - gastrointestinal higher lower

    - cardiovascular higher/ lower lower/ higher

    Drug cost/ 3 months

    lower

    higher

    12

    Preliminary review

    Which one is better? NSAID or COX-2

    Which one is cheaper? NSAID or COX-2

    Which one will you select? NSAID or COX-2

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    In sum

    We have limited money/ resources.

    We have choices of how to use the money.

    When we use money for one choice, we lose

    opportunity to use for another choice.

    We have to make decision on choosing for a moreworthwhile of money used.

    Outcomes of choices are multiple ones. We need a method to combine outcomes before

    comparing between the choices.

    13

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    Economic Burden

    to the Society

    Obat Yang Rasional: Safe, Effective,Acceptable PENINGKATAN

    KESEJAHTERAAN PASIEN

    ACCESSIBLE

    DISEASE BURDEN

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    Reeder CE. Overview of pharmacoeconomics and pharmaceutical outcomes

    evaluations. Am. J. Health Syst. Pharm. 1995;52(suppl_4):S5-8.

    Pharmacoeconomics:

    Pharmacoeconomics may be defined as balancing the

    costwith the consequences (outcomes) ofpharmaceutical therapies and services.

    As a type of outcomes evaluation, pharmacoeconomics

    looks beyond just the direct cost of a pharmaceutical by

    including its impact on total health resource utilizationand costs.

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    Health economics is a discipline that analyses

    the economic aspects of health and healthcareand that usually focuses on the costs

    (inputs) and the consequences (outcomes) of

    health care interventions using methods and

    theories from economics and medicine.

    Berger et al 2003.

    Economic evaluation is the comparative

    analysis of alternative courses of action in

    terms of both their costs and consequences.

    Drummond et al 2005.

    17

    EE_TP_theory.pptx

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    Why study Pharmacoeconomics?

    Health Expenditures as a % of GDP by Country

    0.02.0

    4.0

    6.0

    8.0

    10.0

    12.014.0

    16.0

    18.0

    1970

    1975

    1980

    1985

    1990

    1995

    2000

    2005

    Year

    %G

    DP

    Canada

    France

    Germany

    Japan

    United Kingdom

    United States

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    But when it comes to outcomes

    Life Expectancy at Birth by Country

    60

    63

    66

    69

    72

    75

    78

    81

    84

    1961

    1966

    1971

    1976

    1981

    1986

    1991

    1996

    2001

    2004

    YEAR

    YearsofLife CanadaFrance

    Germany

    Japan

    UK

    US

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    So

    What are we doing wrong?

    And how can we improve ourperformance?

    by spending less

    getting better outcomes

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    Pharmacoeconomics allows us

    to compare the economic resources consumed

    (inputs) to produce the health and economic

    consequences of products or services

    (outcomes).

    INPUTS OUTCOMES

    Economic Health and EconomicResources Consequences

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    Patient

    Outcomes

    Clinical

    Economic

    HumanisticPathogens

    Socio-economic factors

    Technology

    Healthcare facilities

    Health financing

    Outcomes in health care (ECHO model)

    22

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    Outcomesof Health Care

    Clinical outcomes;mortality, morbidity, disability, clinical end points e.g.

    blood pressure, serum glucose concentrations.

    Humanistic outcomes;

    effects on physical, social, and emotional well-being e.g.

    patient satisfaction, QALYs (Quality-adjusted life years).

    Economic outcomes;

    impact on total health resource utilization and cost e.g.savings (change) on treatment cost due to clinical

    pharmacy services.

    23

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    24

    Economic evaluation (EE)

    The comparative analysis of alternative

    courses of action in terms of both their costs

    and consequences.

    Choice

    Program A

    Program B

    Consequences A

    Consequences B

    Cost A

    Cost B

    EE_TP_theory.pptx

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    25

    25

    Principles of EE

    CostsoftheoptionEffectivenessoftheoption

    Lower

    Higher

    LowerHigher

    EE

    EE(rare case)

    Accept

    Reject

    EE_TP_theory.pptx

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    2. Identify the perspective

    that is, who will be utilizing the information to

    make whatdecisions.

    This will guide you in choosing the relevant

    costs and benefits.

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    Perspectives

    1. Patient

    2. Health Practitioner

    3. Hospitals or Hospital systems

    4. Third-Party payers

    5. Societal

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    Patient Perspective

    Examples of costs that directly affectthe patient include:

    Out-of-Pocket costs

    lost income transportation

    Relevant Consequences are: Therapeutic effectiveness Adverse events Quality of Life (QOL)

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    Health Practitioner

    Costs to physicians may include:

    Hospitalization

    Pharmacy

    Personnel

    Supplies

    Consequences of interest are:

    Therapeutic effectiveness

    Adverse events

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    Hospitals

    Costs include:

    Hospital stay costs

    Treatment of adverse events & complications

    Consequences of interest:

    Therapeutic effectiveness

    Adverse events

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    Third-Party Payer

    Costs of care incurred for covered serviceswhich may include:

    Hospitalization

    Pharmacy

    Nursing home care

    Consequences of interest None

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    Societal

    All possible costs including lost productivity

    All possible consequences including QoL, & lifeyears.

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    Cost factors are becoming more

    important

    From whose perspective?

    Health provider?

    Patient?

    Societal (masyarakat)?

    Payer?

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    Biaya (cost) didefinisikan sebagai besarnya

    sumber daya (resources) yang dikonsumsi

    Biaya produk atau pelayanan merupakan nilai

    moneter dari sumber daya yang dikonsumsi

    dalam menghasilkan barang atau jasa

    Sumber daya antara lain: sdm, sarana prasarana,

    gedung

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    Macam-macam biaya

    Biaya Langsung (Direct Cost)

    Biaya Tak Langsung (Indirect Cost)

    Biaya Tak Teraba (Intangible Cost)

    Biaya Tetap (Fixed Cost) Biaya Tidak Tetap (Variable Cost)

    Biaya rata-rata (Average Cost)

    Biaya marjinal (Marginal Cost)

    Cost of illness Cost of therapy

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    Quote of the day

    adai membuat pohon memiliki

    akar yang lebih dalam dan kuat

    (Dolly Parton, Singer, Amerika)