Download - Raimund Ubar
Tallinn University of TechnologyDepartment of Computer Engineering
Tallinn, September 16, 2013CEBE IAB-meeting
CEBE – Centre of Excellence for “Integrated Electronic Systems and
Biomedical Engineering“
Raimund Ubar
CEBE IAB-Meeting
Integreeritud elektroonikasüsteemide ja biomeditsiinitehnika tippkeskus© Raimund Ubar
International Advisory Board
WELCOME to TallinnMarta Rencz - Budapest University of Technology, HungaryBashir M. Al-Hashimi - University of Southampton, UKJürgen Bommer - Dialysezentrum Heidelberg, GermanyBernard Courtois - CMP, FranceRainer Dorsch - Bosch, GermanyManfred Glesner - TU Darmstadt, GermanyAhmed Jerraya - CEA-LETI, MINATEC, FranceJaakko Malmivuo - Tampere University of Technology, FinlandUwe Pliquett - Institut für Bioprozess- und Analytische Messtechnik, Germany
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Integreeritud elektroonikasüsteemide ja biomeditsiinitehnika tippkeskus© Raimund Ubar
Welcome
09:00 R.Ubar General Overview about CEBE
Presentations09:30 J.RaikResearch on Verification and Diagnosis FP7 DIAMOND
09:55 A.Jutman Research on Testing. FP7 BASTION
10:20 -10:50 Coffee
10:50 M.MinResearch on Signal Processing Cooperation with ELIKO Presentations
11:20 I.FridolinResearch on Biomedical Engineering Cooperation with hospitals
11:50 DISCUSSIONS
12:30 -14:00 Lunch
14:00 -15:30 Open lecture of Dr. Honoris Causa of TUT R. Kurki-Suonio
16:00 – 17:30 Discussions between IAB and CEBE management
Program
Integreeritud elektroonikasüsteemide ja biomeditsiinitehnika tippkeskus© Raimund Ubar
Overview
General about CEBE (position in Estonia, structure, research fields, new project activities, mission)
Slogan of CEBE – HEALTH2
Two types of synergy Overview about cooperation in CEBE Formal results (PhD defences, patents,
publications, projects, external cooperation)
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Integreeritud elektroonikasüsteemide ja biomeditsiinitehnika tippkeskus© Raimund Ubar
How CEBE Was Born
National program (EU Structural Funds):
„Development of Centres of Excellence in Research“
Period: 2008-2015
Number of candidates – 24
Each consortium consisted of research groups who had a target financed project (financed from Ministry of Education)
7 + 5 centres (in 2011) were selected
CEBE is one of the 12 Centres
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Integreeritud elektroonikasüsteemide ja biomeditsiinitehnika tippkeskus© Raimund Ubar
Estonian 12 Excellence Centres
2008
Tartu Genomics Chemical Biology Bio-diversity Research Translational Medicine Theory of Culture
Tallinn Computer Science CEBE
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2011
Tartu Mesosystems Dark Matter in Particle
Physics and Cosmology Environmental Adaptation High-Technology Materials
for Sustainable Development
Tallinn Nonlinear Studies
Integreeritud elektroonikasüsteemide ja biomeditsiinitehnika tippkeskus© Raimund Ubar
Mission of CEBE
Mission: Improvement of the quality of life through research and technological innovation Electronics and signal processing
Thomas Johan Seebeck Dept. of Electronics, TUT System design, test, and diagnostics
Dept. of Computer Engineering, TUT Engineering in biology and medicine
Technomedicum, TUT
Application directions: Mission-critical and dependable embedded systems Advancing medical-, food- and biotechnology Methods, algorithms & tools in signal processing, signal
interpretation, design of embedded systems, test and verification
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Integreeritud elektroonikasüsteemide ja biomeditsiinitehnika tippkeskus© Raimund Ubar
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CEBE Steering Committee
Tallinn University of Technology
TJS DE DCE TM
CEBE Cooperation Projects
Structure of CEBE
IABARCHIMEDES
Integreeritud elektroonikasüsteemide ja biomeditsiinitehnika tippkeskus© Raimund Ubar
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Financial sources 2010 2011-2013 (average)
CEBE budget 583 29,6% 555 30,7%
Estonian sources 600 30,5% 513 28,3%
European projects 784 39,9% 743 41,0%
Total 1.967 100% 1.812 100%
Number of part-time researchers: 45 (22 full positions with average salary of 1400 Eur per month)
Number of doctorands: 64
Budget (thousands euros per year):
People and Budget
Integreeritud elektroonikasüsteemide ja biomeditsiinitehnika tippkeskus© Raimund Ubar
CEBE Competences
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Optical analysis
for dialysis
Interpretation of Biosignals
Investigation of brain signals
(EEG)
Quality of blood vessels
Impedance spectroscopy
Cardiacmonitors, stimulators
Signal processing algorithms
Semiconductor technology
Integreeritud elektroonikasüsteemide ja biomeditsiinitehnika tippkeskus© Raimund Ubar
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Health Risk Prevention by Technology
Sensors, equipments
Health diagnosis
toolDoctorsRisk
factorsRisks
Biosignals Healthcare plan
Integreeritud elektroonikasüsteemide ja biomeditsiinitehnika tippkeskus© Raimund Ubar
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eHealthMiddleware
Internet Gateway
Local DataConcentrator
Ambient Assisting Technologies
Generic Distributed ES Architectures
Integreeritud elektroonikasüsteemide ja biomeditsiinitehnika tippkeskus© Raimund Ubar
Slogan of CEBE - Health2
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Nested Health2 Management Concept
Medical equipments,
ICT
DOCTOR
PATIENT
Patient’s Health
Biomedical engineering
Design, Development
Repair
Test, VerificationDiagnosis
System Health
Medical knowledge
Integreeritud elektroonikasüsteemide ja biomeditsiinitehnika tippkeskus© Raimund Ubar
Bioimpedancespectrography& tomography
Brain research, EEG spectral
analysis
Optical dialysis monitoring
Optical pulse wave measurement
in arteries
Research in biomedical engineering
Signal processing algorithms
Design for low power, speed, cost, reliability
System design
Design of dedicated processors
Verification, design error automated
diagnosis and repair
Design for dependability
Automated testing and fault diagnosis
CEBE Research Towards Health2
Pacemakers
Mobile EEG analyser
Equipments foroptical signal measurement
Medical equipment
Applications
Information for doctors
Bioimpedance analysers
Integreeritud elektroonikasüsteemide ja biomeditsiinitehnika tippkeskus© Raimund Ubar
CEBE research topics
Verification, test and diagnosis (R.Ubar, J.Raik, A.Jutman)
Design of Embedded Systems (P.Ellervee, G.Jervan, Th.Hollstein)
Signal processing and bio-impedance spectroscopy (M.Min)
Semiconductor technology (T.Rang)
Optical Methods in Cardiology (K.Meigas)
Optical Methods in Dialysis (I.Fridolin)
Interpretation of Brain EEG Signals (H.Hinrikus)
Looking for Synergy > Internal Projects
P1
P2
P5
P4
P6
P3
P7
P8 Platform for Embedded System Design
Integreeritud elektroonikasüsteemide ja biomeditsiinitehnika tippkeskus© Raimund Ubar
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Cooperation Synergy
External impact:Applications
ComputerEngineering
Electronics
Technomedicum
EXPECTATIONs:(Two goals of CEBE)
Research excellence
Applications
Internal impact:Improved Research
Excellence
Integreeritud elektroonikasüsteemide ja biomeditsiinitehnika tippkeskus© Raimund Ubar
Cooperation Projects P1. Application Specific Processors for Signal Processing
in Biomedicine (E/CE – M.Min)
Results: Methods of signal generation and processing for broad-band impedance spectroscopy with implementations in medicine and engineering
New specific signal processor architectures (P.Ellervee)
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Products:Pacemakers (Cooperation with St.Jude Medical, USA)
Impedance-spectroscopy measurement equipment QUADRA (Cooperation with Enterprise Estonia, start-up company Prototuba OÜ)
Inventor prof. Mart Min was nominated among 3 selected candidates for the European Inventor Award 2011
Integreeritud elektroonikasüsteemide ja biomeditsiinitehnika tippkeskus© Raimund Ubar
Cooperation Projects
P2. Verification, debug, DFT of Systems (CE: D/V – R.Ubar/J.Raik)
Results: Methods for verification and automated debug of systems (J.Raik, M.Jenihhin)
Prototype: Fast fault simulator (speed-up 5-10 times, compared to commercial analogs) (S.Devadze)
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ROx xRIy
ySSBDDT)(
New testability marker, easily to be calculated from the circuit structure
Characterizes the circuit complexity
Integreeritud elektroonikasüsteemide ja biomeditsiinitehnika tippkeskus© Raimund Ubar
Cooperation Projects
P2. Verification, debug, DFT (CE: D/V – R.Ubar/J.Raik)
Result: New family of benchmark circuits ordered by the complexity (by the values of the testability marker)
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a...
.
. b...
.
.
bk...
.
.
be...
.
.
bs...
.
.
c...
.
. d...
.
. de...
.
.
Shared preprocessorand integrator
Common buffersfor all channels
Shared prepocessorand shared integrator
Common buffersfor all channels
Shared preprocessor
Sharedpreprocessor
Shared adder/subtractorin the preprocessor
Initial design
Shared adder/subtractorin the preprocessor
and shared integrator
Added buffersfor every samplefor every channel
Sharing of resources Increase of complexity Complexity
Cost of processing (time)
Test generationFault simulationTest length
Integreeritud elektroonikasüsteemide ja biomeditsiinitehnika tippkeskus© Raimund Ubar
Cooperation Projects
P2. Verification, debug, DFT (CE: D/V – R.Ubar/J.Raik)
Result: Novel at-speed on-line functional test method for signal processors (by using inherent specific signals instead of LFSRs or ATPG tests) (M.Gorev)
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Signal processor
LFSR
Sine
Chirp
Sawtooth
Fault coverage
Test length
Integreeritud elektroonikasüsteemide ja biomeditsiinitehnika tippkeskus© Raimund Ubar
HLDD Verification and Design Repair
Bug
P2. Verification, debug, DFT of systems
Specification
ImplementationSpecification Implementation
Decision Diagrams
Each graph is represented by unique polynomialsas a canonical model of the system
Novelty: A new possibility for formal verification of digital systems, design error detection and automated repair
Integreeritud elektroonikasüsteemide ja biomeditsiinitehnika tippkeskus© Raimund Ubar
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Managing the Complexity with HLDDs
A=FA1 (...)
B=FB1 (...)
C=FC1 (...)
A=FA2 (B,C,...)
A=FAn (D,E,...)
State space
Program data flow
Behavior of A
DE
B
C
High-Level Decision Diagrams
Novelty: Instead of reasoning the design as a whole, it will be partitioned into the behavioral sub-models of functional variables (HLDDs)
Integreeritud elektroonikasüsteemide ja biomeditsiinitehnika tippkeskus© Raimund Ubar
Cooperation Projects
P3. Total Peripheral Resistance (E/TM – K.Meigas)
Results: Methods for continuous and noninvasive optical monitoring of blood pressure and diagnosis of atherosclerosis
Distinguishing high sudden death risk patients in various heart diseases
Product:Software for commercial Holter monitor devices
By spin-off company Tensiotrace OÜ, Estonia
Clinical experiments in the hospital PERH, Estonia
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Integreeritud elektroonikasüsteemide ja biomeditsiinitehnika tippkeskus© Raimund Ubar
Cooperation Projects
P4. Evaluation of mental disorders using EEG analyser (CE/TM – M.Jenihhin/H.Hinrikus)
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Results: EEG spectral asymmetry index was invented (SASI algorithm), which allowed to develop a new method for determining depressive disorders by measuring EEG signals of the brain (H.Hinrikus)
Prototype: Portable EEG analyzer for detecting mental disorders (M.Jenihhin)
Clinical experiments are going on
Integreeritud elektroonikasüsteemide ja biomeditsiinitehnika tippkeskus© Raimund Ubar
Cooperation Projects P5. Reliable and disturbance free monitoring of dialysis
(CE/TM – I.Fridolin)
Results: Methods for multicomponent monitoring of uremic toxins in biofluids during dialysis
Product:
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Medical equipment for dialysis dose monitoring DiasensBy Enterprise Estonia, AS Ldiamon
Integreeritud elektroonikasüsteemide ja biomeditsiinitehnika tippkeskus© Raimund Ubar
Cooperation Projects P6. Testing of electronic systems (E/CE
– A.Jutman) Results: Methods and a system for automated test program
synthesis for electronic boards Methods and high-performance embedded instrumentation in
electronic boards Products:
• Microprocessor models for testing• Embedded instrumentation IPs for testing of PCBs and IC chips
(Göpel Electronics GmbH, Germany)• BERT (Bit-Error-Rate) Test Equipment
(CERN, Switzerland)
By spin-off Testonica Lab, Estonia 26
Integreeritud elektroonikasüsteemide ja biomeditsiinitehnika tippkeskus© Raimund Ubar
Cooperation Projects
P7. Semiconductor Technology (T.Rang) Results: Two new approaches have been developed to increase
the yield in manufacturing of high speed GaAs power diodes
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Cooperation partners:• Ioffe Physical-Technical Inst. of
Russian Acad. of Sciences,• Power Electronics Dept. (TUT)
Products: High speed power GaAs
structures using the LPE technology By By Clifton Ltd, Estonia
Integreeritud elektroonikasüsteemide ja biomeditsiinitehnika tippkeskus© Raimund Ubar
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Cooperation Projects
Defect0101
Conditional faultPattern fault
Constrained SAFSingle faulty signal
Resistive bridge fault
X-faultByzantine fault
BridgesStuck-opens
Multiple faulty signal
SAF
Multiple fault
P7. Semiconductor Technology (T.Rang, R.Ubar)
Goals: Defect-oriented Testing with advanced fault models
Integreeritud elektroonikasüsteemide ja biomeditsiinitehnika tippkeskus© Raimund Ubar
Dependable ES Design Platform
Novel methods in design for dependability:
Platform based design environment for dependable embedded systems Fault simulation Automated synthesis and
analysis of test programs System verification and design
error diagnosis Automated design error repair Dependability of NoC-based
System-on-Chips
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Algorithms, solutions
Signal source,sensors
Design space exploration
Prototype
Architectures,components
Integreeritud elektroonikasüsteemide ja biomeditsiinitehnika tippkeskus© Raimund Ubar
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Behavioral VHDL-Design
RTL VHDL-Design
High-Level Synthesis TTU
Logic-Level Synthesis Synopsys/Cadence
VHDL > DD
DD
Gate-Level EDIF Netlist
EDIF > SSBDD
SSBDD
Logic-Level ATPG TURBO-TESTER
Test
Hierarchical ATPG
DECIDER
EDIF ISCAS
Converter
Defect-Level ATPG DOT
Defect Library
ISCAS Netlist
University Software
Defect-Fault Analysis
TU Warsaw
ZamiaCAD Design FrameworkTTU/IBM/Zamia cooperation
HardwareVerificationFramework
APRICOT
Defect level
High level
Logic level
D&T Environment for Research
Possibility for wide range of experimental
scenarios
Integreeritud elektroonikasüsteemide ja biomeditsiinitehnika tippkeskus© Raimund Ubar
Europrojects during 2011-2015 FP7: - SAFEMETAL (2010 - 2012) FP7: - CREDES (2010 - 2012) FP7: Diagnosis, Error Modelling and Correction for Reliable Systems
Design - DIAMOND (2011 - 2013) FP7: - Innovative, Highly Efficient Road Surface Measurement and
Control System - HERMES (2012 - 2014) FP7: BASTION (2014 - 2016) – (CEBE + Testonica Lab)
Organized international conferences Baltic Electronic Conferences (2008, 2010, 2012) Nordic Test Forum (2011) IEEE Norchip Conference (2012), IEEE DDECS Workshop (2012) BELAS – European – LatinAmerican Workshop (2013) HiPEAC Computing Systems Week (2013)
CEBE International Cooperation
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Integreeritud elektroonikasüsteemide ja biomeditsiinitehnika tippkeskus© Raimund Ubar
Cooperation Partners of CEBE
The partners of CEBE in Estonian industry
• ELIKO, Artec Group, Smartimplant, Cybernetica AS, National Semiconductor Eesti, Clifton AS, JR Medical, Elcoteq, AS LDI, LDIAMON AS, Emros OÜ, Tensiotrace OÜ, Girf OÜ, AB Medical Teeninduse OÜ, a.o.
• 2 clinics , 4 Estonian hospitals International cooperation
• IBM, Ericsson, St. Jude Medical, Boston Scientific, National Semiconductor, Analog Devices, TDI Inc, Göpel Electronic, STMicroelectronics, AerieLogic, TransEda, a.o.
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Integreeritud elektroonikasüsteemide ja biomeditsiinitehnika tippkeskus© Raimund Ubar
Concluding Statistics
Some numbers about CEBE (last 4/5 years): 13 international projects (5 FP7), 25+ national grants 25 PhD thesis defended 452 publications (170 journal and 273 conf. papers) Cooperation with 10 industrial partners from Estonia and more
than 30 institutions from 15 countries 15 patents and 11 patent applications Spin-off companies: 4 (Testonica Lab, Tensiotrace OÜ,
Optofluid Technologies OÜ, Prototuba OÜ) Products: 9 International evalvation of CEBE (End of 2011)
Grade: 5 - Excellent (Application was 4,5)
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Thank you!