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Bahasa, dokter anak, psikolog, ahli bedah telinga, hidung dan tenggorokan dan
manajer koordinator.
3.2 Saran
Setelah mendapatkan hasil sintesa jurnal, maka ada beberapa hal yang dapat
dikembangkan, antara lain perlu dilakukan penelitian lebih lanjut tentang pengaruh
polusi lingkungan (paparan peptisida) dan perokok pasif terhadap tingkat kejadian
cleft lip and palate.
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DAFTAR PUSTAKA
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3. Paiva KBS, Maas CS, Santos PM dos, Granjeiro JM, Letra A. Extracellular
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4. Hlongwa P, Levin J, Rispel LC. Epidemiology and clinical profile of
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5. Gajera M, Desai N, Suzuki A, Li A, Zhang M, Jun G, et al. MicroRNA-655-3p
and microRNA-497-5p inhibit cell proliferation in cultured human lip cells
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8. Martín-Del-Campo M, Rosales-Ibañez R, Rojo L. Biomaterials for cleft lip and
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Olvera-Molina S, Orozco-Martín MA, et al. Prevalence of orofacial clefts and
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10. Carlson JC, Nidey NL, Butali A, Buxo CJ, Christensen K, Deleyiannis FWD,
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11. Worley ML, Patel KG, Kilpatrick LA. Cleft Lip and Palate. Clin Perinatol
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12. Tajrin A, Ruslin M, Fauzi A, Rasul MI, Kawulusan N, Alim NN. Pencegahan
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13. Kunjana T, Zuliyanto A. Studi Komparatif Kejadian Celah Orofasial Menurut
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14. Gasca-Sanchez FM, Santos-Guzman J, Elizondo-Dueñaz R, Mejia-Velazquez
GM, Ruiz-Pacheco C, Reyes-Rodriguez D, et al. Spatial clusters of children
with cleft lip and palate and their association with polluted zones in the
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15. Vass G, Mohos G, Bere Z, Ivan L, Varga J, Piffko J, et al. Secondary
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16. Minatel L, Marcela de Luna Gomes J, Aparecido Araújo Lemos C, Justino de
Oliveira Limírio JP, Pellizzer EP. Influence of vomer flap on craniofacial
growth in patients with cleft lip and palate: A systematic review. J Cranio-
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17. Burg ML, Chai Y, Yao CA, Magee W, Figueiredo JC. Epidemiology, etiology,
and treatment of isolated cleft palate. Front Physiol. 2016;7(MAR):1–16.
18. Hooper JE, Feng W, Li H, Leach SM, Phang T, Siska C, et al. Systems biology
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19. Krugman ME. An overview of cleft lip and palate. J South Calif Dent
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20. Agbenorku P. Orofacial Clefts: A Worldwide Review of the Problem. ISRN
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21. Shaye D, Liu CC, Tollefson TT. Cleft Lip and Palate. An Evidence-Based
Review. Facial Plast Surg Clin North Am [Internet]. 2015;23(3):357–72.
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22. Allori AC, Mulliken JB, Meara JG, Shusterman S, Marcus JR. Classification
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of cleft lip/palate: Then and now. Cleft Palate-Craniofacial J. 2017;54(2):175–
88.
23. Elsherbiny A, Mazeed AS. Comprehensive and reliable classification system
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24. Koch H, Grzonka M, Koch J. Cleft malformation of lip, alveolus, hard and soft
palate, and nose (LAHSN)-a critical view of the terminology, the diagnosis
and gradation as a basis for documentation and therapy. Br J Oral Maxillofac
Surg. 1995;33(1):51–8.
25. Saleem K, Zaib T, Sun W, Fu S. Assessment of candidate genes and genetic
heterogeneity in human non syndromic orofacial clefts specifically non
syndromic cleft lip with or without palate. Heliyon [Internet].
2019;5(12):e03019. Available from:
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26. Leslie EJ, Marazita ML. Genetics of cleft lip and cleft palate. Am J Med Genet
Part C Semin Med Genet. 2013;163(4):246–58.
27. Leal MFC, Lemos A, Costa GF, Lopes Cardoso I. Genetic And Environmental
Factors Involved In The Development Of Oral Malformations Such As Cleft
Lip/Palate In Non-Syndromic Patients And Open Bite Malocclusion. Eur J
Med Heal Sci. 2020;2(3).
28. Campos Neves ATS de, Marçal Vieira EM, Fabio Aranha AM, Borba AM,
Borges ÁH, Ricci Volpato LE. Cleft lip and palate: Associated genetic and
environmental factorsImmunodeficiency Virus. Sci J Dent. 2015;2(September
2016):19–25.
29. Zhang JX, Arneja JS. Evidence-Based Medicine: The Bilateral Cleft Lip
Repair. Plast Reconstr Surg. 2017;140(1):152e-165e.
30. Martelli DRB, Coletta RD, Oliveira EA, Swerts MSO, Rodrigues LAM,
Oliveira MC, et al. Association between maternal smoking, gender, and cleft
lip and palate. Braz J Otorhinolaryngol [Internet]. 2015;81(5):514–9. Available
from: http://dx.doi.org/10.1016/j.bjorl.2015.07.011
31. Setó-Salvia N, Stanier P. Genetics of cleft lip and/or cleft palate: Association
with other common anomalies. Eur J Med Genet [Internet]. 2014;57(8):381–
93. Available from: http://dx.doi.org/10.1016/j.ejmg.2014.04.003
32. Razil Goveas S, Savitha NS. Role of Environmental Factors in the Etiology of
Non-syndromic Cleft Lip Palate. 21 21 Int J Sci Study [Internet].
2017;4(12):12. Available from: www.ijss-sn.com
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33. Shi M, Christensen K, Weinberg CR, Romitti P, Bathum L, Lozada A, et al.
Orofacial cleft risk is increased with maternal smoking and specific
detoxification-gene variants. Am J Hum Genet. 2007;80(1):76–90.
34. Kawalec A, Nelke K, Pawlas K, Gerber H. Risk factors involved in orofacial
cleft predisposition-review. Open Med. 2015;10(1):163–75.
35. Gunnerbeck A, Bonamy AKE, Wikström AK, Granath F, Wickström R,
Cnattingius S. Maternal snuff use and smoking and the risk of oral cleft
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36. Kummet CM, Moreno LM, Wilcox AJ, Romitti PA, Deroo LA, Munger RG, et
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International Population-Based Study. Am J Epidemiol. 2016;183(9):834–41.
37. Joubert BR, Felix JF, Yousefi P, Bakulski KM, Just AC, Breton C, et al. DNA
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38. Bell JC, Raynes-Greenow C, Turner RM, Bower C, Nassar N, O’Leary CM.
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Epidemiol. 2014;28(4):322–32.
39. Bille C, Olsen J, Vach W, Knudsen VK, Olsen SF, Rasmussen K, et al. Oral
clefts and life style factors - A case-cohort study based on prospective Danish
data. Eur J Epidemiol. 2007;22(3):173–81.
40. Li S, Chao A, Li Z, Moore CA, Liu Y, Zhu J, et al. Folic acid use and
nonsyndromic orofacial clefts in China: A prospective cohort study.
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41. Vujkovic M, Ocke MC, Van Der Spek PJ, Yazdanpanah N, Steegers EA,
Steegers-Theunissen RP. Maternal western dietary patterns and the risk of
developing a cleft lip with or without a cleft palate. Vol. 110, Obstetrics and
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42. Pi X, Jin L, Li Z, Liu J, Zhang Y, Wang L, et al. Association between
concentrations of barium and aluminum in placental tissues and risk for
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43. Mehrotra D. Genomic expression in non syndromic cleft lip and palate
patients: A review. J Oral Biol Craniofacial Res [Internet]. 2015;5(2):86–91.
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44. Lesmana S, Auerkari EI. Genes contributing in cleft lip and cleft palate: A
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literature review. J Int Dent Med Res. 2016;9(Specialissue):441–8.
45. Berkowitz S. Cleft Lip and Palate: Diagnosis and Management. 3rd Ed. San
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46. Teja Chitturi R, Ramana Reddy BV. Genetic Aspects of Cleft Lip and Palate ?
A Review. JBR J Clin Diagnosis Res. 2014;02(01):10–3.
47. Cesario JM, Malt AL, Deacon LJ, Sandberg M, Vogt D, Tang Z, et al. Lhx6
and Lhx8 promote palate development through negative regulation of a cell
cycle inhibitor gene, p57Kip2. Hum Mol Genet. 2015;24(17):5024–39.
48. Setó-Salvia N, Stanier P. Genetics of cleft lip and/or cleft palate: Association
with other common anomalies. Eur J Med Genet [Internet]. 2014;57(8):381–
93. Available from: http://dx.doi.org/10.1016/j.ejmg.2014.04.003
49. Leslie EJ, Marazita ML. Genetics of cleft lip and cleft palate. Am J Med Genet
Part C Semin Med Genet. 2013;163(4):246–58.
50. Nahai FR, Williams JK, Burstein FD, Martin J, Thomas J. The Management of
Cleft Lip and Palate: Pathways for Treatment and Longitudinal Assessment.
Semin Plast Surg. 2005;19(04):275–85.
51. Kati FA. Cleft Lip and Palate : Review Article. World J Pharm Med Res.
2018;4(7):155–63.
52. Esenlik E, Gibson T, Kassam S, Sato Y, Garfinkle J, Figueroa AA, et al. NAM
Therapy—Evidence-Based Results. Cleft Palate-Craniofacial J.
2020;57(4):529–31.
53. Gill DS, Naini FB. The Multidisciplinary Management of Cleft Lip and Palate
Deformity. Orthod Princ Pract. 2013;99(10):254–62.
54. Tse R. Unilateral cleft lip: Principles and practice of surgical management.
Semin Plast Surg. 2012;26(4):145–55.
55. Agrawal K. Cleft palate repair and variations. Indian J Plast Surg.
2009;42(SUPPL. 1).
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LAMPIRAN
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Lampiran 1. Surat Penugasan
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Lampiran 2. Surat Seminar Proposal/ Ujian 1
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Lampiran 3. Surat Seminar Hasil/ Ujian 2
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Lampiran 5. Dokumentasi